Date published: 2026-5-17

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Ceramide phosphorylethanolamine

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Alternate Names:
1-(2-Aminoethly)-phosphoryl-ceramide
Application:
Ceramide phosphorylethanolamine is a sphingolipid with an ethanolamine base
Purity:
≥98%
Molecular Weight:
689.00
Molecular Formula:
C38H77N2O6P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ceramide phosphorylethanolamine, also known as CPE, is a lipid molecule that belongs to the family of sphingolipids. It is composed of a sphingosine backbone attached to a fatty acid and a phosphorylethanolamine group. Ceramides are important components of cell membranes and play a role in maintaining their structure and integrity. They are involved in various cellular processes, including cell signaling, cell proliferation, differentiation, and apoptosis (programmed cell death). Ceramides are also implicated in several physiological and pathological conditions, such as aging, cancer, and neurodegenerative diseases.


Ceramide phosphorylethanolamine References

  1. Formation of ceramide phosphorylethanolamine from phosphatidylethanolamine in the rumen protozoon Entodinium caudatum (Short Communication).  |  Broad, TE. and Dawson, RM. 1973. Biochem J. 134: 659-62. PMID: 16742830
  2. The microaerophilic flagellate, Trichomonas vaginalis, contains unusual acyl lipids but no detectable cardiolipin.  |  Guschina, IA., et al. 2009. J Eukaryot Microbiol. 56: 52-7. PMID: 19335774
  3. Sphingobacterium kyonggiense sp. nov., isolated from chloroethene-contaminated soil, and emended descriptions of Sphingobacterium daejeonense and Sphingobacterium mizutaii.  |  Choi, HA. and Lee, SS. 2012. Int J Syst Evol Microbiol. 62: 2559-2564. PMID: 22180612
  4. Crystal structure of RahU, an aegerolysin protein from the human pathogen Pseudomonas aeruginosa, and its interaction with membrane ceramide phosphorylethanolamine.  |  Kočar, E., et al. 2021. Sci Rep. 11: 6572. PMID: 33753805
  5. Sphingomyelin synthase related protein is a mammalian phosphatidylethanolamine phospholipase C.  |  Chiang, YP., et al. 2021. Biochim Biophys Acta Mol Cell Biol Lipids. 1866: 159017. PMID: 34332077
  6. Sphingomyelin Synthase Family and Phospholipase Cs.  |  Jiang, XC. and Chiang, YP. 2022. Adv Exp Med Biol. 1372: 77-86. PMID: 35503176
  7. Identification of ceramide phosphorylethanolamine and ceramide phosphorylglycerol in the lipids of an anaerobic bacterium.  |  LaBach, JP. and White, DC. 1969. J Lipid Res. 10: 528-34. PMID: 4309192
  8. Metabolism of ceramide phosphorylethanolamine, phosphatidylinositol, phosphatidylserine and phosphatidylglycerol by housefly larvae.  |  Hildenbrandt, GR., et al. 1971. Lipids. 6: 508-16. PMID: 4330548
  9. Occurrence of ceramide phosphorylethanolamine containing hydroxy fatty acid in a bivalve.  |  Itasaka, O., et al. 1973. J Biochem. 73: 191-3. PMID: 4690231
  10. The aminoethylphosphonate-containing lipids of rumen protozoa.  |  Dawson, RM. and Kemp, P. 1967. Biochem J. 105: 837-42. PMID: 4967076
  11. Occurrence and biosynthesis of ceramide phosphorylethanolamine in chicken and rat liver.  |  Muehlenberg, BA., et al. 1972. Can J Biochem. 50: 166-73. PMID: 5014537
  12. Effect of vitamin K depletion and restoration on sphingolipid metabolism in Bacteroides melaninogenicus.  |  Lev, M. and Milford, AF. 1972. J Lipid Res. 13: 364-70. PMID: 5025467
  13. Analysis of phospho- and phosphonosphingolipids by high-performance liquid chromatography.  |  Itasaka, O., et al. 1984. J Biochem. 95: 1671-5. PMID: 6469944
  14. Phospholipid biosynthesis in the anaerobic protozoon Entodinium caudatum.  |  Broad, TE. and Dawson, RM. 1975. Biochem J. 146: 317-28. PMID: 808216
  15. Identification of ceramide-phosphorylethanolamine in oomycete plant pathogens: Pythium ultimum, Phytophthora infestans, and Phytophthora capsici.  |  Moreau, RA., et al. 1998. Lipids. 33: 307-17. PMID: 9560806

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ceramide phosphorylethanolamine, 5 mg

sc-300332
5 mg
$403.00