Date published: 2026-3-3

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Sp1 Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Sp1 monoclonal antibodies for advanced research in gene regulation and transcriptional control. Sp1 monoclonal antibodies are suitable for various applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Sp1, a zinc-finger transcription factor, plays a crucial role in the regulation of numerous genes involved in cellular processes such as growth, differentiation, and apoptosis. Its ability to bind to GC-rich motifs in promoter regions makes Sp1 essential for the transcriptional activation of various target genes, influencing critical pathways in development and disease. Understanding the function of Sp1 is vital for elucidating mechanisms underlying various biological processes and potential therapeutic targets. Sp1 monoclonal antibodies enable researchers to investigate gene expression patterns and regulatory networks in both normal and pathological conditions. Sp1 monoclonal antibodies support detailed analysis of transcription factor dynamics and DNA-binding activities. Santa Cruz Biotechnology monoclonal antibodies for Sp1 research contribute to advancing scientific knowledge in gene regulation and cellular biology.

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Sp1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Sp1 Antibody (1C6)

sc-420mouse IgG1 κ609-627 (h)WB, IP, IF, IHC(P), ELISAm, r, h
356
(21)

Sp1 Antibody (E-3)

sc-17824mouse IgG2a121-345 (h)WB, IP, IF, ELISAm, r, h
136
(15)

Sp1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Sp1 CRISPR/Cas9 KO Plasmid (h)

sc-400166hGene KnockoutGFP0
(0)

Sp1 HDR Plasmid (h)

sc-400166-HDRhHomology Directed RepairPuromycin0
(0)

Sp1 CRISPR/Cas9 KO Plasmid (m)

sc-423094mGene KnockoutGFP
1
(0)

Sp1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Sp1 CRISPR Activation Plasmid (h)

sc-400166-ACThGene ActivationPuro, Blast, Hygro0
(0)

Sp1 CRISPR Activation Plasmid (h2)

sc-400166-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Sp1 CRISPR Activation Plasmid (m)

sc-423094-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

Sp1 CRISPR Activation Plasmid (m2)

sc-423094-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

Sp1 Lentiviral Activation Particles (m)

sc-423094-LACmGene ActivationPuro, Blast, Hygro
1
(0)

Sp1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Sp1 siRNA (h)

sc-29487hGene SilencingN/A
111
(2)

Sp1 siRNA (h2)

sc-44221hGene SilencingN/A
1
(0)

Sp1 shRNA Plasmid (h)

sc-29487-SHhGene SilencingPuromycin
111
(2)

Sp1 shRNA Plasmid (h2)

sc-44221-SHhGene SilencingPuromycin
1
(0)

Sp1 shRNA (h) Lentiviral Particles

sc-29487-VhGene SilencingPuromycin
111
(2)

Sp1 shRNA (h2) Lentiviral Particles

sc-44221-VhGene SilencingPuromycin
1
(0)

Sp1 siRNA (m)

sc-29488mGene SilencingN/A
20
(0)

Sp1 shRNA Plasmid (m)

sc-29488-SHmGene SilencingPuromycin
20
(0)

Sp1 shRNA (m) Lentiviral Particles

sc-29488-VmGene SilencingPuromycin
20
(0)

Sp1 siRNA (r)

sc-61895rGene SilencingN/A
8
(0)

Sp1 shRNA Plasmid (r)

sc-61895-SHrGene SilencingPuromycin
8
(0)

Sp1 shRNA (r) Lentiviral Particles

sc-61895-VrGene SilencingPuromycin
8
(0)

Sp1 siRNA (bovine)

sc-270564bovineGene SilencingN/A
1
(0)

Sp1 shRNA Plasmid (bovine)

sc-270564-SHbovineGene SilencingPuromycin
1
(0)

Sp1 shRNA (bovine) Lentiviral Particles

sc-270564-VbovineGene SilencingPuromycin
1
(0)

Sp1 Oligonucleotides

Empty Table HeaderProduct NameCONSENSUS CAT. #MUTANT CAT. #MUTANT CONSENSUSBINDING MOTIFCitationsRATING

Sp1 consensus oligonucleotide

sc-2502sc-25035′-ATT CGA TCG GGG CGG GGC GAG C-3′"GG"→"TT"
258
(0)