Date published: 2025-12-16

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SMG CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. SMG gene silencers are available as SMG CRISPR/Cas9 Knockout plasmids and SMG Double Nickase Plasmids. SMG CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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SMG CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SMG1 CRISPR/Cas9 KO Plasmid (h)

sc-404760hGene KnockoutGFP0
(0)

SMG1 HDR Plasmid (h)

sc-404760-HDRhHomology Directed RepairPuromycin0
(0)

SMG1 Double Nickase Plasmid (h)

sc-404760-NIChGene KnockoutPuromycin0
(0)

SMG1 Double Nickase Plasmid (h2)

sc-404760-NIC-2hGene KnockoutPuromycin0
(0)

SMG1 CRISPR/Cas9 KO Plasmid (m)

sc-433296mGene KnockoutGFP0
(0)

SMG1 HDR Plasmid (m)

sc-433296-HDRmHomology Directed RepairPuromycin0
(0)

SMG1 Double Nickase Plasmid (m)

sc-433296-NICmGene KnockoutPuromycin0
(0)

SMG1 Double Nickase Plasmid (m2)

sc-433296-NIC-2mGene KnockoutPuromycin0
(0)

SMG5 CRISPR/Cas9 KO Plasmid (h)

sc-406989hGene KnockoutGFP0
(0)

SMG5 HDR Plasmid (h)

sc-406989-HDRhHomology Directed RepairPuromycin0
(0)

SMG5 Double Nickase Plasmid (h)

sc-406989-NIChGene KnockoutPuromycin0
(0)

SMG5 Double Nickase Plasmid (h2)

sc-406989-NIC-2hGene KnockoutPuromycin0
(0)

SMG5 CRISPR/Cas9 KO Plasmid (m)

sc-432861mGene KnockoutGFP0
(0)

SMG5 HDR Plasmid (m)

sc-432861-HDRmHomology Directed RepairPuromycin0
(0)

SMG5 Double Nickase Plasmid (m)

sc-432861-NICmGene KnockoutPuromycin0
(0)

SMG5 Double Nickase Plasmid (m2)

sc-432861-NIC-2mGene KnockoutPuromycin0
(0)

SMG6 CRISPR/Cas9 KO Plasmid (h)

sc-411705hGene KnockoutGFP0
(0)

SMG6 HDR Plasmid (h)

sc-411705-HDRhHomology Directed RepairPuromycin0
(0)

SMG6 Double Nickase Plasmid (h)

sc-411705-NIChGene KnockoutPuromycin0
(0)

SMG6 Double Nickase Plasmid (h2)

sc-411705-NIC-2hGene KnockoutPuromycin0
(0)

SMG6 CRISPR/Cas9 KO Plasmid (m)

sc-430478mGene KnockoutGFP0
(0)

SMG6 HDR Plasmid (m)

sc-430478-HDRmHomology Directed RepairPuromycin0
(0)

SMG6 Double Nickase Plasmid (m)

sc-430478-NICmGene KnockoutPuromycin0
(0)

SMG6 Double Nickase Plasmid (m2)

sc-430478-NIC-2mGene KnockoutPuromycin0
(0)

SMG7 CRISPR/Cas9 KO Plasmid (h)

sc-411377hGene KnockoutGFP0
(0)

SMG7 HDR Plasmid (h)

sc-411377-HDRhHomology Directed RepairPuromycin0
(0)

SMG7 Double Nickase Plasmid (h)

sc-411377-NIChGene KnockoutPuromycin0
(0)

SMG7 Double Nickase Plasmid (h2)

sc-411377-NIC-2hGene KnockoutPuromycin0
(0)

SMG7 CRISPR/Cas9 KO Plasmid (m)

sc-432633mGene KnockoutGFP0
(0)

SMG7 HDR Plasmid (m)

sc-432633-HDRmHomology Directed RepairPuromycin0
(0)

SMG7 Double Nickase Plasmid (m)

sc-432633-NICmGene KnockoutPuromycin0
(0)

SMG7 Double Nickase Plasmid (m2)

sc-432633-NIC-2mGene KnockoutPuromycin0
(0)

SMG8 CRISPR/Cas9 KO Plasmid (h)

sc-408902hGene KnockoutGFP0
(0)

SMG8 HDR Plasmid (h)

sc-408902-HDRhHomology Directed RepairPuromycin0
(0)

SMG8 Double Nickase Plasmid (h)

sc-408902-NIChGene KnockoutPuromycin0
(0)

SMG8 Double Nickase Plasmid (h2)

sc-408902-NIC-2hGene KnockoutPuromycin0
(0)

SMG9 CRISPR/Cas9 KO Plasmid (h)

sc-412649hGene KnockoutGFP0
(0)

SMG9 HDR Plasmid (h)

sc-412649-HDRhHomology Directed RepairPuromycin0
(0)

SMG9 Double Nickase Plasmid (h)

sc-412649-NIChGene KnockoutPuromycin0
(0)

SMG9 Double Nickase Plasmid (h2)

sc-412649-NIC-2hGene KnockoutPuromycin0
(0)

SMG CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SMG1 CRISPR Activation Plasmid (h)

sc-404760-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMG1 CRISPR Activation Plasmid (h2)

sc-404760-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMG1 Lentiviral Activation Particles (h)

sc-404760-LAChGene ActivationPuro, Blast, Hygro0
(0)

SMG1 Lentiviral Activation Particles (h2)

sc-404760-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SMG1 CRISPR Activation Plasmid (m)

sc-433296-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SMG1 CRISPR Activation Plasmid (m2)

sc-433296-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SMG1 Lentiviral Activation Particles (m)

sc-433296-LACmGene ActivationPuro, Blast, Hygro0
(0)

SMG1 Lentiviral Activation Particles (m2)

sc-433296-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SMG5 CRISPR Activation Plasmid (h)

sc-406989-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMG5 CRISPR Activation Plasmid (h2)

sc-406989-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMG5 Lentiviral Activation Particles (h)

sc-406989-LAChGene ActivationPuro, Blast, Hygro0
(0)

SMG5 Lentiviral Activation Particles (h2)

sc-406989-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SMG5 CRISPR Activation Plasmid (m)

sc-432861-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SMG5 CRISPR Activation Plasmid (m2)

sc-432861-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SMG5 Lentiviral Activation Particles (m)

sc-432861-LACmGene ActivationPuro, Blast, Hygro0
(0)

SMG5 Lentiviral Activation Particles (m2)

sc-432861-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SMG6 CRISPR Activation Plasmid (h)

sc-411705-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMG6 CRISPR Activation Plasmid (h2)

sc-411705-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMG6 Lentiviral Activation Particles (h)

sc-411705-LAChGene ActivationPuro, Blast, Hygro0
(0)

SMG6 Lentiviral Activation Particles (h2)

sc-411705-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SMG6 CRISPR Activation Plasmid (m)

sc-430478-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SMG6 CRISPR Activation Plasmid (m2)

sc-430478-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SMG6 Lentiviral Activation Particles (m)

sc-430478-LACmGene ActivationPuro, Blast, Hygro0
(0)

SMG6 Lentiviral Activation Particles (m2)

sc-430478-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SMG7 CRISPR Activation Plasmid (h)

sc-411377-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMG7 CRISPR Activation Plasmid (h2)

sc-411377-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMG7 Lentiviral Activation Particles (h)

sc-411377-LAChGene ActivationPuro, Blast, Hygro0
(0)

SMG7 Lentiviral Activation Particles (h2)

sc-411377-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SMG7 CRISPR Activation Plasmid (m)

sc-432633-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SMG7 CRISPR Activation Plasmid (m2)

sc-432633-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SMG7 Lentiviral Activation Particles (m)

sc-432633-LACmGene ActivationPuro, Blast, Hygro0
(0)

SMG7 Lentiviral Activation Particles (m2)

sc-432633-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

SMG8 CRISPR Activation Plasmid (h)

sc-408902-ACThGene ActivationPuro, Blast, Hygro0
(0)

SMG8 CRISPR Activation Plasmid (h2)

sc-408902-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMG8 Lentiviral Activation Particles (h)

sc-408902-LAChGene ActivationPuro, Blast, Hygro0
(0)

SMG8 Lentiviral Activation Particles (h2)

sc-408902-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SMG9 CRISPR Activation Plasmid (h2)

sc-412649-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SMG9 Lentiviral Activation Particles (h)

sc-412649-LAChGene ActivationPuro, Blast, Hygro0
(0)

SMG9 Lentiviral Activation Particles (h2)

sc-412649-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

C19orf61 CRISPR Activation Plasmid (h)

sc-412649-ACThGene ActivationPuro, Blast, Hygro0
(0)