Sln1 Activators
Sln1 is a histidine kinase that is involved in the HOG signaling pathway, which is responsible for the cellular response to osmotic stress. Sln1 can be activated by a variety of chemicals, including lithium chloride, forskolin, staurosporine, wortmannin, rapamycin, U0126, zymolyase, sorbitol, NaCl, KCl, MgCl2, and CaCl2.
Some chemicals, such as lithium chloride, forskolin, and staurosporine, directly activate Sln1 by inhibiting kinases that negatively regulate Sln1 activity. Other chemicals, such as wortmannin, rapamycin, and U0126, indirectly activate Sln1 by inhibiting signaling pathways that suppress Sln1 activity. Finally, chemicals such as zymolyase, sorbitol, NaCl, KCl, MgCl2, and CaCl2 activate Sln1 by triggering the HOG signaling pathway, which leads to the activation of Sln1.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride (LiCl) is a salt that has been shown to activate Sln1 in a variety of cell types. LiCl can activate Sln1 by inhibiting the GSK3β kinase, which is a negative regulator of Sln1 activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin is a diterpene that has been shown to activate Sln1 in a variety of cell types. Forskolin can activate Sln1 by increasing the levels of cyclic AMP (cAMP), which is a second messenger that can activate various signaling pathways, including the Sln1 activation pathway. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a phosphatidylinositol 3-kinase (PI3K) inhibitor that has been shown to activate Sln1 in a variety of cell types. Wortmannin can activate Sln1 by inhibiting the PI3K signaling pathway, which can lead to the activation of the MAPK signaling pathway, which in turn activates Sln1. | ||||||
Sodium Chloride | 7647-14-5 | sc-203274 sc-203274A sc-203274B sc-203274C | 500 g 2 kg 5 kg 10 kg | $18.00 $23.00 $35.00 $65.00 | 15 | |
NaCl is a salt that can activate Sln1 by increasing the osmolarity of the environment, which triggers the HOG signaling pathway. | ||||||
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $27.00 $34.00 $47.00 $123.00 | 2 | |
MgCl2 is a salt that can activate Sln1 by increasing the osmolarity of the environment, which triggers the HOG signaling pathway. | ||||||
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $65.00 $262.00 | 1 | |
CaCl2 is a salt that can activate Sln1 by increasing the osmolarity of the environment, which triggers the HOG signaling pathway. | ||||||