SLC25A41 Activators
SLC25A41 can play a pivotal role in its function by influencing the cellular availability of ATP, which is the substrate that this mitochondrial transporter protein moves across the mitochondrial membrane. Adenine, as part of ATP, is directly involved in the energy transfer processes of the cell. When adenine levels are high, ATP synthesis is likely to increase, thus providing SLC25A41 with more substrate to transport. Similarly, D-Ribose, by forming the sugar backbone of ATP, can boost the synthesis of this high-energy molecule, indirectly facilitating SLC25A41 activity by augmenting the pool of ATP available for transport. Moreover, Nicotinamide adenine dinucleotide (NAD+) is essential for the oxidative phosphorylation that ultimately leads to ATP production. An increase in NAD+ levels can enhance the electron transport chain's efficiency, thereby boosting ATP synthesis and, consequently, SLC25A41 activation.
Coenzyme Q10 contribute to the electron transport chain and ATP synthesis, which in turn supports SLC25A41 activity. Magnesium chloride provides the necessary magnesium ions that act as cofactors for ATP-binding enzymes, ensuring that ATP is functional and ready for transport by SLC25A41. Antioxidants such as Lipoic acid and Pyrroloquinoline quinone (PQQ) also play a role; the former by acting as a cofactor in energy-producing mitochondrial reactions, and the latter by potentially stimulating mitochondrial biogenesis, leading to an increase in overall mitochondrial function and ATP production. Metabolic intermediates from the Krebs cycle such as Alpha-ketoglutarate, Succinic acid, and Malic acid are crucial in maintaining the flow of the cycle, which is directly tied to the generation of ATP and the subsequent activity of SLC25A41. Lastly, Creatine serves as a temporary storage of phosphate groups in the form of phosphocreatine, which can be quickly mobilized for ATP production, thereby ensuring a steady supply for SLC25A41 to transport.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenine, cell culture grade | 73-24-5 | sc-291834 sc-291834A sc-291834B | 5 g 25 g 100 g | $82.00 $206.00 $546.00 | 2 | |
Adenine is a purine nucleobase and a component of adenosine triphosphate (ATP), the energy currency of the cell. It is integral to various biological processes, including cellular respiration and DNA synthesis. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
NAD+ is a coenzyme that participates in redox reactions, essential in cellular respiration and energy production. It cycles between oxidized (NAD+) and reduced (NADH) states during metabolic processes. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
Coenzyme Q10 is a component of the electron transport chain in mitochondria, essential for the production of ATP. It also serves as an antioxidant, protecting cells from oxidative damage. | ||||||
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $27.00 $34.00 $47.00 $123.00 | 2 | |
Magnesium chloride is a source of magnesium, a vital cofactor for many enzymes, including those necessary for ATP synthesis. It also plays roles in neuromuscular conduction, protein synthesis, and many other cellular functions. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
Lipoic acid is a mitochondrial compound that acts as an antioxidant and is also involved in energy metabolism, particularly in the conversion of pyruvate to acetyl-CoA, a critical step in the production of ATP. | ||||||
Vitamin B12 | 68-19-9 | sc-296695 sc-296695A sc-296695B sc-296695C sc-296695D sc-296695E | 100 mg 1 g 5 g 25 g 100 g 1 kg | $39.00 $55.00 $204.00 $877.00 $3414.00 $9180.00 | 2 | |
Cyanocobalamin, or vitamin B12, is essential for proper nerve function and the production of DNA and red blood cells. It is involved in the metabolism of every cell of the body, especially affecting DNA synthesis and regulation, fatty acid synthesis, and energy production. | ||||||
Pyrroloquinoline quinone | 72909-34-3 | sc-210178 | 1 mg | $238.00 | ||
PQQ is a redox cofactor and an antioxidant that supports mitochondrial biogenesis, potentially leading to improved energy metabolism and increased ATP production. | ||||||
α-Ketoglutaric Acid | 328-50-7 | sc-208504 sc-208504A sc-208504B sc-208504C sc-208504D sc-208504E sc-208504F | 25 g 100 g 250 g 500 g 1 kg 5 kg 16 kg | $32.00 $42.00 $62.00 $108.00 $184.00 $724.00 $2050.00 | 2 | |
Alpha-ketoglutarate is a key intermediate in the Krebs cycle, which is pivotal for energy production in the form of ATP within the mitochondria. It is also involved in amino acid metabolism and the regulation of the body's acid-base balance. | ||||||
Succinic acid | 110-15-6 | sc-212961B sc-212961 sc-212961A | 25 g 500 g 1 kg | $44.00 $74.00 $130.00 | ||
Succinic acid is a dicarboxylic acid that plays a role in the Krebs cycle, a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate derived from carbohydrates, fats, and proteins into carbon dioxide and water. | ||||||
Malic acid | 6915-15-7 | sc-257687 | 100 g | $127.00 | 2 | |
Malic acid is a component of the Krebs cycle, which is vital for cellular respiration and energy production. It is also used to improve athletic performance and reduce fatigue after exercise. | ||||||