Date published: 2026-1-9

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SIMP CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. SIMP gene silencers are available as SIMP CRISPR/Cas9 Knockout plasmids and SIMP Double Nickase Plasmids. SIMP CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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SIMP CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SIMP CRISPR/Cas9 KO Plasmid (h2)

sc-404481-KO-2hGene KnockoutGFP0
(0)

SIMP HDR Plasmid (h2)

sc-404481-HDR-2hHomology Directed RepairPuromycin0
(0)

SIMP Double Nickase Plasmid (h)

sc-404481-NIChGene KnockoutPuromycin0
(0)

SIMP Double Nickase Plasmid (h2)

sc-404481-NIC-2hGene KnockoutPuromycin0
(0)

SIMP CRISPR/Cas9 KO Plasmid (m)

sc-427007mGene KnockoutGFP
1
(0)

SIMP HDR Plasmid (m)

sc-427007-HDRmHomology Directed RepairPuromycin
1
(0)

SIMP Double Nickase Plasmid (m)

sc-427007-NICmGene KnockoutPuromycin
1
(0)

SIMP Double Nickase Plasmid (m2)

sc-427007-NIC-2mGene KnockoutPuromycin
1
(0)

SIMPL CRISPR/Cas9 KO Plasmid (h)

sc-407437hGene KnockoutGFP0
(0)

SIMPL HDR Plasmid (h)

sc-407437-HDRhHomology Directed RepairPuromycin0
(0)

SIMPL Double Nickase Plasmid (h)

sc-407437-NIChGene KnockoutPuromycin0
(0)

SIMPL Double Nickase Plasmid (h2)

sc-407437-NIC-2hGene KnockoutPuromycin0
(0)

SIMPL CRISPR/Cas9 KO Plasmid (m)

sc-425749mGene KnockoutGFP0
(0)

SIMPL HDR Plasmid (m)

sc-425749-HDRmHomology Directed RepairPuromycin0
(0)

SIMPL Double Nickase Plasmid (m)

sc-425749-NICmGene KnockoutPuromycin0
(0)

SIMPL Double Nickase Plasmid (m2)

sc-425749-NIC-2mGene KnockoutPuromycin0
(0)

SIMP CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SIMP CRISPR Activation Plasmid (h)

sc-404481-ACThGene ActivationPuro, Blast, Hygro0
(0)

SIMP CRISPR Activation Plasmid (h2)

sc-404481-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SIMP Lentiviral Activation Particles (h)

sc-404481-LAChGene ActivationPuro, Blast, Hygro0
(0)

SIMP Lentiviral Activation Particles (h2)

sc-404481-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SIMP CRISPR Activation Plasmid (m)

sc-427007-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

SIMP CRISPR Activation Plasmid (m2)

sc-427007-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

SIMP Lentiviral Activation Particles (m)

sc-427007-LACmGene ActivationPuro, Blast, Hygro
1
(0)

SIMP Lentiviral Activation Particles (m2)

sc-427007-LAC-2mGene ActivationPuro, Blast, Hygro
1
(0)

SIMPL CRISPR Activation Plasmid (h)

sc-407437-ACThGene ActivationPuro, Blast, Hygro0
(0)

SIMPL CRISPR Activation Plasmid (h2)

sc-407437-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SIMPL Lentiviral Activation Particles (h)

sc-407437-LAChGene ActivationPuro, Blast, Hygro0
(0)

SIMPL Lentiviral Activation Particles (h2)

sc-407437-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SIMPL CRISPR Activation Plasmid (m)

sc-425749-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SIMPL CRISPR Activation Plasmid (m2)

sc-425749-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SIMPL Lentiviral Activation Particles (m)

sc-425749-LACmGene ActivationPuro, Blast, Hygro0
(0)

SIMPL Lentiviral Activation Particles (m2)

sc-425749-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)