Date published: 2026-5-1

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SIM CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. SIM gene silencers are available as SIM CRISPR/Cas9 Knockout plasmids and SIM Double Nickase Plasmids. SIM CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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SIM CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SIM2s CRISPR/Cas9 KO Plasmid (h2)

sc-405609-KO-2hGene KnockoutGFP0
(0)

SIM2s HDR Plasmid (h2)

sc-405609-HDR-2hHomology Directed RepairPuromycin0
(0)

SIM2s Double Nickase Plasmid (h)

sc-405609-NIChGene KnockoutPuromycin0
(0)

SIM2s Double Nickase Plasmid (h2)

sc-405609-NIC-2hGene KnockoutPuromycin0
(0)

SIM CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SIM1 CRISPR Activation Plasmid (h)

sc-405931-ACThGene ActivationPuro, Blast, Hygro0
(0)

SIM1 Lentiviral Activation Particles (h)

sc-405931-LAChGene ActivationPuro, Blast, Hygro0
(0)

SIM2s CRISPR Activation Plasmid (h)

sc-405609-ACThGene ActivationPuro, Blast, Hygro0
(0)

SIM2s CRISPR Activation Plasmid (h2)

sc-405609-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)