Ser/Thr Protein Kinase Inhibitors
Items 261 to 270 of 284 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PHT-427 | 1191951-57-1 | sc-364582 sc-364582A | 10 mg 50 mg | $68.00 $405.00 | ||
PHT-427 is a potent modulator of Ser/Thr protein kinases, characterized by its ability to engage in specific hydrogen bonding and hydrophobic interactions within the kinase domain. This compound demonstrates unique allosteric effects, altering enzyme conformation and enhancing substrate affinity. Its kinetic profile reveals a non-linear inhibition pattern, suggesting complex regulatory dynamics that can influence downstream signaling cascades and cellular responses. | ||||||
7-Aminoindole | 5192-04-1 | sc-257005 | 1 g | $555.00 | ||
7-Aminoindole serves as a potent modulator of Ser/Thr protein kinases, characterized by its ability to engage in specific hydrogen bonding interactions within the enzyme's active site. This compound alters the phosphorylation landscape by stabilizing certain conformations, thereby affecting substrate accessibility. Its unique structural features contribute to a nuanced kinetic profile, allowing for selective inhibition that can fine-tune various signaling pathways and cellular responses. | ||||||
UCN-02 | 121569-61-7 | sc-202377 sc-202377A sc-202377B | 500 µg 1 mg 5 mg | $220.00 $400.00 $1600.00 | 1 | |
UCN-02 is a selective inhibitor of Ser/Thr protein kinases, distinguished by its unique ability to form covalent bonds with key cysteine residues in the kinase domain. This interaction leads to a conformational shift that disrupts ATP binding, effectively modulating kinase activity. Its distinct molecular architecture allows for precise targeting of specific kinases, influencing downstream signaling cascades and cellular processes with remarkable specificity and efficiency. | ||||||
PKC α (C2-4) inhibitor peptide | sc-3094 | 0.5 mg/0.1 ml | $95.00 | 1 | ||
PKC α (C2-4) inhibitor peptide is a potent modulator of Ser/Thr protein kinase activity, characterized by its ability to selectively disrupt protein-protein interactions within signaling pathways. This peptide engages in specific non-covalent interactions with the kinase domain, altering its conformation and inhibiting substrate phosphorylation. Its unique sequence and structural features enable it to fine-tune cellular signaling dynamics, impacting various regulatory mechanisms with high specificity. | ||||||
PKC peptide inhibitor, Cell Permeable | sc-3093 | 0.5 mg/0.1 ml | $95.00 | 1 | ||
PKC peptide inhibitor, Cell Permeable, is a selective antagonist of Ser/Thr protein kinases, designed to penetrate cellular membranes effectively. It exhibits unique binding affinity for the regulatory sites of PKC isoforms, leading to conformational changes that hinder enzymatic activity. This inhibitor modulates downstream signaling cascades by disrupting critical phosphorylation events, thereby influencing cellular responses and maintaining homeostasis through precise molecular interactions. | ||||||
PKC ε Translocation negative control | sc-3100 | 1 mg | $95.00 | |||
PKC ε Translocation negative control is a specialized Ser/Thr protein kinase that plays a pivotal role in cellular signaling pathways. It selectively interacts with specific phospholipid membranes, facilitating its translocation and activation. This control mechanism is crucial for regulating kinase activity, as it influences substrate specificity and reaction kinetics. By modulating protein interactions and phosphorylation states, it maintains cellular balance and responsiveness to environmental cues. | ||||||
PKC η Pseudo-substrate inhibitor | sc-3096 | 0.5 mg (lyophilized) | $95.00 | 3 | ||
PKC η Pseudo-substrate inhibitor is a selective Ser/Thr protein kinase that modulates intracellular signaling by mimicking substrate interactions. Its unique binding affinity disrupts the kinase's catalytic activity, influencing downstream signaling cascades. This inhibitor alters the phosphorylation landscape, impacting cellular processes such as growth and differentiation. By stabilizing specific conformations, it fine-tunes the kinase's regulatory mechanisms, ensuring precise control over cellular responses. | ||||||
CaM Kinase ll Inhibitor | sc-3039 | 0.5 mg/0.1 ml | $95.00 | 2 | ||
CaM Kinase II Inhibitor is a selective Ser/Thr protein kinase that disrupts calcium/calmodulin-dependent signaling pathways. It binds to the regulatory domain of CaM Kinase II, preventing its activation and altering its conformational dynamics. This inhibition affects the enzyme's ability to phosphorylate target proteins, thereby modulating various cellular functions. The inhibitor's unique interaction profile allows for fine-tuning of kinase activity, impacting processes like synaptic plasticity and memory formation. | ||||||
Rp-8-Hexylaminoadenosine 3′,5′-monophosphorothioate | sc-391034 | 5 µmol | $562.00 | |||
Rp-8-Hexylaminoadenosine 3′,5′-monophosphorothioate acts as a potent Ser/Thr protein kinase modulator, influencing phosphorylation cascades through its unique binding affinity. By mimicking ATP, it engages in specific interactions with the kinase's active site, altering substrate recognition and catalytic efficiency. This compound's distinct structural features enable it to selectively inhibit or activate various signaling pathways, thereby impacting cellular processes such as growth and differentiation. | ||||||
5-Amino-2-methylindole | 7570-49-2 | sc-254764 | 5 g | $83.00 | ||
5-Amino-2-methylindole serves as a selective modulator of Ser/Thr protein kinases, engaging in unique molecular interactions that enhance or inhibit kinase activity. Its structural conformation allows for precise binding to the enzyme's active site, influencing substrate specificity and reaction kinetics. This compound's ability to stabilize or destabilize enzyme-substrate complexes can lead to significant alterations in downstream signaling pathways, affecting cellular responses and regulatory mechanisms. | ||||||