Date published: 2025-10-25

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SEMA4A Inhibitors

SEMA4A inhibitors belong to a distinct chemical class designed to modulate the activity of Semaphorin 4A (SEMA4A), a transmembrane protein that plays a crucial role in cellular processes such as axon guidance, immune response, and organ development. The term "SEMA4A" stands for Semaphorin 4A, a member of the semaphorin family of proteins, which are known for their involvement in cellular communication and regulation. These inhibitors are meticulously crafted molecules designed to interfere with the signaling pathways associated with SEMA4A, thereby influencing cellular behavior in a targeted manner.

SEMA4A inhibitors typically comprises specific pharmacophores that interact with the active sites of the SEMA4A protein, disrupting its normal function. The inhibition of SEMA4A is thought to impact cellular processes mediated by semaphorin signaling, particularly those related to cell migration, proliferation, and differentiation. By selectively blocking the activity of SEMA4A, these inhibitors have the potential to unveil new insights into the intricate mechanisms governing cellular behavior. Researchers are actively exploring the biochemical pathways affected by SEMA4A inhibitors to gain a deeper understanding of their impact on cellular physiology. As a novel class of compounds, SEMA4A inhibitors hold promise for elucidating the intricate regulatory networks in which semaphorins participate, shedding light on fundamental biological processes and providing valuable tools for basic research in cell biology and related fields.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PP 2

172889-27-9sc-202769
sc-202769A
1 mg
5 mg
$92.00
$223.00
30
(1)

An Src family kinase inhibitor, PP2 can interrupt signaling cascades that may involve SEMA4A due to its role in modulating cytoskeletal organization.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

JNK inhibitor, SP600125 can alter signaling pathways that SEMA4A may participate in, particularly in immune response and axon guidance.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

This MEK inhibitor can also interfere with potential SEMA4A-ERK pathway interactions.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

As an mTOR inhibitor, rapamycin may affect the signaling pathways that SEMA4A is part of, particularly in cell growth and proliferation.