Date published: 2026-4-1

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SCO2 Inhibitors

The chemical class referred to as SCO2 inhibitors encompasses a diverse group of organic compounds that are characterized by their ability to interact with and modulate the activity of the Synthesis of Cytochrome C Oxidase 2 (SCO2) enzyme. SCO2 is a crucial factor in the intricate process of cytochrome c oxidase (COX) assembly within the mitochondrial respiratory chain. Inhibitors belonging to this class are meticulously designed to interact with specific binding sites on the SCO2 enzyme, disrupting its normal functioning and potentially influencing COX assembly and mitochondrial respiration.

These inhibitors can be composed of various molecular structures, including small organic molecules and inorganic compounds, each tailored to interact with the enzyme's active sites or binding pockets. By interfering with SCO2, these inhibitors hold the potential to unravel the intricate regulatory mechanisms underlying COX assembly and mitochondrial energy metabolism. Ongoing research in this area aims to elucidate the precise molecular interactions between SCO2 and its inhibitors, contributing to a deeper understanding of mitochondrial bioenergetics and cellular physiology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Vitamin B12

68-19-9sc-296695
sc-296695A
sc-296695B
sc-296695C
sc-296695D
sc-296695E
100 mg
1 g
5 g
25 g
100 g
1 kg
$60.00
$90.00
$325.00
$1155.00
$3851.00
$10056.00
2
(1)

Certain forms of vitamin B12 have been explored as potential SCO2 inhibitors due to their interaction with the enzyme's active site, which is involved in the incorporation of copper ions into COX.

Acetazolamide

59-66-5sc-214461
sc-214461A
sc-214461B
sc-214461C
sc-214461D
sc-214461E
sc-214461F
10 g
25 g
100 g
250 g
500 g
1 kg
2 kg
$81.00
$177.00
$434.00
$541.00
$883.00
$1479.00
$2244.00
1
(1)

Acetazolamide is a carbonic anhydrase inhibitor that has been investigated for its effects on mitochondrial function, including potential interactions with SCO2.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol, a natural polyphenol found in foods like grapes and red wine, has been studied for its potential to affect mitochondrial function, including potential interactions with SCO2.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin, a compound found in turmeric, has been investigated for its effects on mitochondrial function and potential interactions with SCO2.