Date published: 2025-10-25

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SCD3 Inhibitors

Common SCD3 Inhibitors include, but are not limited to CAY 10566 CAS 944808-88-2, A 922500 CAS 959122-11-3, CDDO Methyl Ester CAS 218600-53-4, Myriocin (ISP-1) CAS 35891-70-4 and Betulinic Acid CAS 472-15-1.

SCD3 inhibitors constitute a distinct category of chemical compounds that are specifically designed to interact with and modulate the function of stearoyl-CoA desaturase 3 (SCD3), an enzyme crucially involved in fatty acid metabolism. SCD3 plays a pivotal role in the biosynthesis of monounsaturated fatty acids by catalyzing the conversion of saturated fatty acids into their corresponding monounsaturated forms. This enzymatic activity contributes to the regulation of lipid composition within cellular membranes and has implications for various biological processes, including membrane fluidity, lipid signaling, and energy storage. Inhibitors targeting SCD3 are developed with the intention of binding to specific regions of the enzyme's structure, altering its activity and impacting lipid metabolic pathways.

The interaction between SCD3 inhibitors and the stearoyl-CoA desaturase 3 enzyme offers a valuable avenue for exploring the intricate web of lipid metabolism and its effects on cellular function. By modulating the activity of SCD3, these inhibitors provide insights into the mechanisms governing the balance between saturated and monounsaturated fatty acids, a process that has implications for cellular physiology and homeostasis. The study of SCD3 inhibitors enhances our understanding of the complex interplay between lipid metabolism and various cellular processes, ranging from energy regulation to membrane dynamics. Furthermore, this chemical class contributes to unraveling the connections between lipid-related disorders and cellular responses, revealing novel insights into metabolic diseases and lipid-associated pathologies.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

CAY 10566

944808-88-2sc-205109
sc-205109A
sc-205109B
1 mg
5 mg
25 mg
$115.00
$502.00
$1497.00
4
(1)

CAY10566 is a selective SCD inhibitor that might impact SCD3 by inhibiting its desaturase activity and influencing fatty acid metabolism.

A 922500

959122-11-3sc-203793
10 mg
$265.00
2
(1)

A-922500 is a SCD inhibitor that might affect SCD3 by modulating its desaturase activity and influencing fatty acid metabolism.

CDDO Methyl Ester

218600-53-4sc-504720
10 mg
$220.00
(0)

CDDO-Me is a triterpenoid compound that might indirectly influence SCD3 expression and function through modulation of related signaling pathways.

Myriocin (ISP-1)

35891-70-4sc-201397
10 mg
$106.00
8
(2)

Myriocin is a serine palmitoyltransferase inhibitor that might indirectly affect SCD3 function by modulating ceramide and lipid metabolism.

Betulinic Acid

472-15-1sc-200132
sc-200132A
25 mg
100 mg
$115.00
$337.00
3
(1)

Betulinic acid might indirectly influence SCD3 expression and function through modulation of related signaling pathways involved in lipid metabolism.

Ursodeoxycholic acid

128-13-2sc-204935
sc-204935A
1 g
5 g
$51.00
$128.00
4
(0)

UDCA might indirectly impact SCD3 expression and function by modulating bile acid metabolism and related signaling pathways.

C75 (racemic)

191282-48-1sc-202511
sc-202511A
sc-202511B
1 mg
5 mg
10 mg
$71.00
$202.00
$284.00
9
(1)

C75 is a FAS inhibitor that might indirectly affect SCD3 expression and function through its impact on fatty acid synthesis and metabolism.