Date published: 2026-2-8

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RPE65 Antibodies

Santa Cruz Biotechnology features a diverse variety of RPE65 monoclonal antibodies for research focused on understanding RPE65 protein function. RPE65 monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).RPE65 is a crucial protein involved in the visual cycle, specifically in the conversion of all-trans-retinal to 11-cis-retinal, which is essential for the regeneration of visual pigments in photoreceptor cells. Mutations in the RPE65 gene are associated with inherited retinal diseases, such as Leber congenital amaurosis and retinitis pigmentosa, highlighting its importance in vision and eye health. Understanding the function and regulation of RPE65 can provide insights into potential therapeutic strategies for retinal conditions. RPE65 research has revealed significant implications for developing treatments targeting visual impairments. Ongoing studies continue to uncover new aspects of RPE65's role in maintaining healthy vision. Current investigations focus on understanding how RPE65 dysfunction leads to various eye disorders. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of RPE65 and its impact on vision health.

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RPE65 Antibodies

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RPE65 Antibody (E-5)

sc-390787mouse IgG1 κ445-470 (h)WB, IP, IF, ELISAm, r, h
10
(4)

RPE65 Antibody (8B11)

sc-53489mouse IgG1 κFL (bovine)WB, IP, IFm, r, h
5
(1)

RPE65 Antibody (3D9)

sc-73616mouse IgG1 κFL (bovine)WB, IP, IFm, r, h
4
(1)

RPE65 CRISPR Knockout, HDR and Double Nickase Plasmids

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RPE65 CRISPR/Cas9 KO Plasmid (h)

sc-401489hGene KnockoutGFP0
(0)

RPE65 HDR Plasmid (h)

sc-401489-HDRhHomology Directed RepairPuromycin0
(0)

RPE65 CRISPR/Cas9 KO Plasmid (m)

sc-422705mGene KnockoutGFP0
(0)

RPE65 HDR Plasmid (m)

sc-422705-HDRmHomology Directed RepairPuromycin0
(0)

RPE65 CRISPR Activation Products

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RPE65 CRISPR Activation Plasmid (h)

sc-401489-ACThGene ActivationPuro, Blast, Hygro0
(0)

RPE65 CRISPR Activation Plasmid (h2)

sc-401489-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

RPE65 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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RPE65 siRNA (h)

sc-44898hGene SilencingN/A0
(0)

RPE65 shRNA Plasmid (h)

sc-44898-SHhGene SilencingPuromycin0
(0)

RPE65 shRNA (h) Lentiviral Particles

sc-44898-VhGene SilencingPuromycin0
(0)

RPE65 siRNA (m)

sc-44899mGene SilencingN/A0
(0)

RPE65 shRNA Plasmid (m)

sc-44899-SHmGene SilencingPuromycin0
(0)

RPE65 shRNA (m) Lentiviral Particles

sc-44899-VmGene SilencingPuromycin0
(0)