Date published: 2025-9-30

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Rock Inhibitors

Santa Cruz Biotechnology now offers a broad range of Rock inhibitors for use in various applications. Rock inhibitors are chemical compounds that target Rho-associated protein kinases (ROCKs), which are critical enzymes involved in regulating the cytoskeleton and cellular processes such as contraction, motility, proliferation, and apoptosis. These inhibitors are widely utilized in scientific research to dissect the roles of ROCKs in cell biology and to explore their influence on cellular signaling pathways. They are especially valuable in studies focusing on cell migration, adhesion, and morphological changes, providing insights into fundamental biological processes and disease mechanisms. Researchers employ Rock inhibitors to modulate cellular functions in various model systems, facilitating the exploration of mechanistic pathways and the identification of potential biomarkers or targets for further investigation. The use of Rock inhibitors has been instrumental in advancing our understanding of cellular dynamics and has contributed significantly to the development of new experimental approaches and technologies in the field of cell and molecular biology. View detailed information on our available Rock inhibitors by clicking on the product name.

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Items 11 to 12 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

AS 1892802

928320-12-1sc-396101
5 mg
$206.00
(0)

AS 1892802 acts as a potent modulator of ROCK, exhibiting unique reactivity as an acid halide. Its electrophilic nature allows for rapid acylation of nucleophilic residues, leading to distinct reaction kinetics that influence downstream signaling cascades. The compound's ability to form transient intermediates enhances its interaction with protein targets, promoting conformational changes that affect cellular processes. Additionally, its unique steric properties contribute to selective binding, optimizing its functional impact.

Y-27632-d4

sc-220394
sc-220394A
1 mg
10 mg
$286.00
$2448.00
(0)

Y-27632-d4 exhibits distinctive properties as a ROCK inhibitor, characterized by its isotopic labeling that enhances tracking in biochemical assays. This compound engages in specific hydrogen bonding and hydrophobic interactions, which stabilize its binding to target proteins. Its unique isotopic composition allows for precise kinetic studies, revealing insights into reaction mechanisms. Additionally, the compound's structural rigidity contributes to its selectivity, influencing downstream signaling pathways effectively.