Date published: 2025-10-31

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Rev-erb alpha Activators

Santa Cruz Biotechnology now offers a broad range of Rev-erb alpha Activators for use in various applications. Rev-erb alpha activators are chemical compounds that enhance the activity of the Rev-erb alpha protein, a nuclear receptor involved in regulating circadian rhythms and metabolic processes. In scientific research, these activators are essential tools for studying the complex interactions between circadian biology and metabolism, providing insights into how these systems are interlinked and regulated. They allow researchers to manipulate the function of Rev-erb alpha, helping to study its role in gene expression, lipid metabolism, and the overall maintenance of cellular homeostasis. The availability of high-quality Rev-erb alpha activators from Santa Cruz Biotechnology supports a wide array of research endeavors, from basic biochemical studies to more complex investigations into the modulation of circadian and metabolic pathways. View detailed information on our available Rev-erb alpha Activators by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

GSK4112

1216744-19-2sc-300774
sc-300774A
5 mg
10 mg
$88.00
$202.00
1
(0)

GSK4112 acts as a selective modulator of Rev-erb alpha, showcasing a unique ability to influence circadian rhythm and metabolic processes. Its structural design allows for precise engagement with the ligand-binding domain, promoting conformational changes that alter gene expression. The compound exhibits distinct kinetic properties, enabling rapid cellular uptake and effective pathway modulation. Its interactions with nuclear receptors highlight its role in regulating transcriptional networks, providing insights into cellular homeostasis.

YC-1

170632-47-0sc-202856
sc-202856A
sc-202856B
sc-202856C
1 mg
5 mg
10 mg
50 mg
$32.00
$122.00
$214.00
$928.00
9
(1)

YC-1 indirectly activates Rev-erbα by influencing its stabilization and nuclear localization.

Hemin chloride

16009-13-5sc-202646
sc-202646A
sc-202646B
5 g
10 g
25 g
$100.00
$157.00
$320.00
9
(1)

Hemin chloride acts as an indirect activator by increasing heme levels, which is a natural ligand of Rev-erbα.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Zinc Protoporphyrin-9 indirectly modulates Rev-erbα activity through heme pathway interference.

Cobalt(II) chloride

7646-79-9sc-252623
sc-252623A
5 g
100 g
$63.00
$173.00
7
(1)

Protoporphyrin IX cobalt chloride indirectly affects Rev-erbα by interacting with heme metabolism.