Recoverin Inhibitors
Recoverin inhibitors are a class of chemical compounds that have garnered significant attention in the field of molecular biology and neuroscience due to their distinctive ability to modulate the activity of a protein known as recoverin. These compounds are characterized by their specific interactions with recoverin, a small calcium-binding protein found predominantly in photoreceptor cells of the retina. Recoverin is a key player in the visual signaling pathway and plays a crucial role in the regulation of phototransduction. Recoverin inhibitors act by binding to recoverin and interfering with its calcium-binding capabilities, ultimately leading to the disruption of its normal function within photoreceptor cells.
The structural diversity within the recoverin inhibitor class is notable, with various chemical entities exhibiting different affinities and modes of interaction with recoverin. Some recoverin inhibitors are small organic molecules, while others may be peptides or larger macromolecules. What makes recoverin inhibitors particularly intriguing is their potential to modulate calcium signaling within photoreceptor cells, which in turn can impact the sensitivity and responsiveness of the visual system.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $59.00 $173.00 | 15 | |
Nifedipine is a dihydropyridine calcium channel blocker that can inhibit the influx of calcium ions, which is crucial for recoverin's calcium-binding ability and subsequent modulation of photoreceptor cells. | ||||||
Diltiazem | 42399-41-7 | sc-204726 sc-204726A | 1 g 5 g | $209.00 $464.00 | 4 | |
Diltiazem is a benzothiazepine calcium channel blocker that can alter the calcium dynamics within cells, potentially inhibiting recoverin's calcium-dependent regulatory role. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is an activator of adenylate cyclase that can increase intracellular cAMP levels, leading to a cascade that can modulate calcium channels and indirectly affect recoverin's activity. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $28.00 $53.00 | 37 | |
2-APB can modulate calcium release from intracellular stores and could alter recoverin's calcium-dependent activities by affecting the calcium concentration. | ||||||
W-7 | 61714-27-0 | sc-201501 sc-201501A sc-201501B | 50 mg 100 mg 1 g | $166.00 $306.00 $1675.00 | 18 | |
W-7 is a calmodulin antagonist that can interfere with calcium signaling pathways, thereby indirectly affecting recoverin's interaction with its targets. | ||||||
Calmidazolium chloride | 57265-65-3 | sc-201494 sc-201494A | 10 mg 50 mg | $156.00 $612.00 | 27 | |
Calmidazolium chloride is another calmodulin antagonist that can disrupt calcium-mediated processes, potentially affecting recoverin's regulatory functions. | ||||||
Ruthenium red | 11103-72-3 | sc-202328 sc-202328A | 500 mg 1 g | $188.00 $250.00 | 13 | |
Ruthenium Red can block calcium channels and inhibit calcium uptake into cells, which can alter recoverin's ability to bind calcium and exert its effects. | ||||||
Ryanodine | 15662-33-6 | sc-201523 sc-201523A | 1 mg 5 mg | $223.00 $799.00 | 19 | |
Ryanodine can affect calcium release from the sarcoplasmic/endoplasmic reticulum, potentially influencing recoverin's activity by altering intracellular calcium levels. | ||||||