RBMS3 Inhibitors
Chemical inhibitors of RBMS3 can target various signaling pathways and cellular processes that the protein is known to be involved with. Marimastat acts by inhibiting matrix metalloproteases, thereby preventing the remodeling of the extracellular matrix, which is essential for cellular signaling pathways that RBMS3 is involved in. LY294002 and Wortmannin are both PI3K inhibitors, and they inhibit RBMS3 by shutting down the PI3K/AKT pathway, leading to a decrease in cell survival and proliferation signals that are necessary for RBMS3's functional role. PD98059 serves as an inhibitor of MEK, blocking the MAPK/ERK pathway and thereby inhibiting transcription factors downstream of RBMS3's RNA binding activity. SP600125, as a JNK inhibitor, disrupts the JNK signaling pathway associated with the regulation of apoptosis, a process in which RBMS3 is implicated through its RNA binding and stabilization capabilities.
Continuing with the inhibition pathways, SB203580 specifically targets p38 MAPK, impacting the inflammatory responses and stress responses that RBMS3 might regulate through RNA processing. U0126, another MEK1/2 inhibitor, impairs the MAPK/ERK signaling pathway, which is crucial for gene expression regulation and cellular proliferation - processes influenced by RBMS3. Rapamycin inhibits mTOR, which has a role in protein synthesis and cell cycle progression, activities in which RBMS3 is involved through RNA binding and modulation. Trichostatin A, by inhibiting histone deacetylase, can alter chromatin structure and gene expression, thereby affecting RBMS3's role in RNA processing. Apigenin inhibits protein kinase CK2, which impacts various cellular pathways including those involving RBMS3. ZM447439 inhibits Aurora kinases, which are key in mitotic progression, a process where RBMS3 may play a role through its RNA stabilization and regulation functions. Lastly, Y-27632, as a ROCK inhibitor, influences cell shape, motility, and contraction, which are potential areas regulated by RBMS3 through its RNA binding activity.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Marimastat | 154039-60-8 | sc-202223 sc-202223A sc-202223B sc-202223C sc-202223E | 5 mg 10 mg 25 mg 50 mg 400 mg | $165.00 $214.00 $396.00 $617.00 $4804.00 | 19 | |
Marimastat is a broad-spectrum matrix metalloprotease (MMP) inhibitor that can inhibit RBM3 by preventing the remodeling of the extracellular matrix, which is crucial for the cellular signaling pathways that RBMS3 is involved in. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that can inhibit RBMS3 by blocking the PI3K/AKT signaling pathway, leading to reduced cell survival and proliferation signals that RBMS3 needs for its function. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is an inhibitor of MEK, which in turn can inhibit RBMS3 by blocking the MAPK/ERK pathway, leading to the inhibition of transcription factors that are downstream of RBMS3's RNA binding activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $65.00 $267.00 | 257 | |
SP600125 is a JNK inhibitor that can inhibit RBMS3 by blocking the JNK signaling pathway, which is involved in the regulation of apoptosis, a process that RBMS3 has been implicated to influence through RNA binding and stabilization. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a specific inhibitor of p38 MAPK that can inhibit RBMS3 by disrupting the p38 MAPK pathway, which influences inflammatory responses and cellular stress responses that RBMS3 might regulate through RNA processing. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a potent PI3K inhibitor that can inhibit RBMS3 by irreversibly inhibiting the PI3K/AKT pathway, which affects cellular processes like cell growth and survival that RBMS3 is indirectly involved with through RNA binding activities. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is a MEK1/2 inhibitor that can inhibit RBMS3 by blocking the MAPK/ERK signaling pathway, which is significant for the regulation of gene expression and cellular proliferation, processes that are influenced by RBMS3's function. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor that can inhibit RBMS3 by inhibiting the mTOR pathway, which plays a role in protein synthesis and cell cycle progression, processes that RBMS3 is involved in through its RNA binding and modulation activity. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor that can inhibit RBMS3 by altering chromatin structure and gene expression, which can indirectly affect RBMS3's role in RNA processing and stabilization. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $32.00 $210.00 $720.00 $1128.00 $2302.00 $3066.00 $5106.00 | 22 | |
Apigenin is a CK2 inhibitor that can inhibit RBMS3 by inhibiting protein kinase CK2, which affects various cellular processes, including those that RBMS3 is involved in through RNA binding and regulation. | ||||||