RbAp46 Inhibitors
RbAp46 inhibitors belong to a chemical class of compounds specifically designed to selectively and reversibly target the protein known as RbAp46 (Retinoblastoma-Binding Protein 7). RbAp46 is an essential component of various chromatin remodeling complexes involved in histone modification and gene regulation. These inhibitors are engineered to interact with RbAp46, potentially interfering with its activity and interactions within chromatin remodeling complexes. The chemical structure of these inhibitors enables them to bind to specific regions or binding sites on RbAp46, thereby modulating its function. By doing so, RbAp46 inhibitors aim to explore the roles of RbAp46 in various cellular processes, including transcriptional regulation and chromatin dynamics.
Researchers utilize RbAp46 inhibitors in biochemical and cellular studies to gain insights into its physiological functions and its potential impact on gene expression and chromatin organization. The design and development of these inhibitors are based on a comprehensive understanding of RbAp46's structural features and its contributions to chromatin-associated processes, providing valuable tools for advancing research in the field of chromatin biology and gene regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(5-Bromopyridin-3-yl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone | 1314241-44-5 | sc-504278 | 10 mg | $330.00 | ||
A synthetic small-molecule compound known to selectively inhibit the interaction between RBAP46 and a histone chaperone, thus affecting chromatin remodeling. | ||||||
UNC1999 | 1431612-23-5 | sc-475314 | 5 mg | $142.00 | 1 | |
This compound is known to inhibit both histone methyltransferase activity and the interaction between RBAP46 and a specific histone methyltransferase. | ||||||
Spironolactone | 52-01-7 | sc-204294 | 50 mg | $109.00 | 3 | |
Known as a potassium-sparing diuretic, Spironolactone has been identified as an inhibitor of RBAP46. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Triptolide has been shown to inhibit RBAP46 and exert anti-inflammatory and anticancer effects. | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $42.00 | 4 | |
Widely used as an anti-inflammatory drug, acetylsalicylic acid has been reported to inhibit RBAP46. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has been identified as an inhibitor of RBAP46 and exhibits various biological activities. | ||||||
Zafirlukast | 107753-78-6 | sc-204942 sc-204942A | 10 mg 100 mg | $37.00 $174.00 | 1 | |
Originally developed as a leukotriene receptor antagonist, Zafirlukast has been shown to inhibit RBAP46. | ||||||
Anacardic Acid | 16611-84-0 | sc-202463 sc-202463A | 5 mg 25 mg | $102.00 $204.00 | 13 | |
Anacardic acid has been reported to inhibit the interaction between RBAP46 and a specific histone acetyltransferase. | ||||||