Date published: 2025-10-18

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Quenchers

Santa Cruz Biotechnology now offers a broad range of quenchers for use in various applications. Quenchers are specialized chemical compounds that play a crucial role in fluorescence-based assays and other biochemical experiments by absorbing fluorescence emitted by reporter molecules. This category of chemicals is essential in scientific research, particularly in the fields of molecular biology, genomics, and proteomics, where precise measurement and control of fluorescence signals are necessary. Quenchers are used to reduce background fluorescence, thereby enhancing the accuracy and sensitivity of quantitative assays, such as real-time PCR, FRET (Frster Resonance Energy Transfer) assays, and DNA sequencing. These compounds enable researchers to monitor biochemical processes in real-time, offering invaluable insights into molecular interactions and dynamic changes within cells. The ability to modulate fluorescence signals with quenchers has made them indispensable tools in the study of gene expression, protein-protein interactions, and the elucidation of complex biological pathways. As a result, quenchers are a fundamental component in advancing scientific knowledge and technological innovations in various research domains. View detailed information on our available quenchers by clicking on the product name.

Items 61 to 62 of 62 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Tide Quencher™ 3 alkyne [TQ3 alkyne]

sc-460818
5 mg
$245.00
(0)

Tide Quencher™ 3 alkyne (TQ3 alkyne) is a distinctive quencher characterized by its unique alkyne structure, which enables selective interactions with excited-state molecules. This compound exhibits rapid reaction kinetics, effectively suppressing fluorescence through efficient energy dissipation pathways. Its ability to form stable complexes with reactive intermediates enhances its performance in quenching applications, making it an essential component for probing intricate molecular interactions in various environments.

5′-DABCYL C6 phosphoramidite

sc-470535
1 g
$1185.00
(0)

5'-DABCYL C6 phosphoramidite serves as a highly effective quencher, distinguished by its unique phosphoramidite backbone that facilitates robust interactions with fluorophores. This compound exhibits a strong ability to absorb energy from excited-state species, leading to efficient fluorescence quenching. Its structural flexibility allows for optimal positioning in nucleic acid constructs, enhancing quenching efficiency and enabling precise control over signal modulation in various experimental setups.