Date published: 2025-10-18

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Quenchers

Santa Cruz Biotechnology now offers a broad range of quenchers for use in various applications. Quenchers are specialized chemical compounds that play a crucial role in fluorescence-based assays and other biochemical experiments by absorbing fluorescence emitted by reporter molecules. This category of chemicals is essential in scientific research, particularly in the fields of molecular biology, genomics, and proteomics, where precise measurement and control of fluorescence signals are necessary. Quenchers are used to reduce background fluorescence, thereby enhancing the accuracy and sensitivity of quantitative assays, such as real-time PCR, FRET (Frster Resonance Energy Transfer) assays, and DNA sequencing. These compounds enable researchers to monitor biochemical processes in real-time, offering invaluable insights into molecular interactions and dynamic changes within cells. The ability to modulate fluorescence signals with quenchers has made them indispensable tools in the study of gene expression, protein-protein interactions, and the elucidation of complex biological pathways. As a result, quenchers are a fundamental component in advancing scientific knowledge and technological innovations in various research domains. View detailed information on our available quenchers by clicking on the product name.

Items 21 to 30 of 62 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

CruzQuench™ 2 CPG 500 Å

sc-362635
100 mg
$195.00
(0)

CruzQuench™ 2 CPG 500 Å is a specialized quencher known for its unique molecular architecture that promotes effective energy transfer dynamics. Its finely tuned pore structure enables enhanced diffusion of excited states, while specific functional groups facilitate strong intermolecular interactions. This compound exhibits rapid reaction kinetics, allowing for efficient energy dissipation through non-radiative pathways, making it ideal for applications requiring precise quenching capabilities.

CruzQuench™ 2 succinimidyl ester

sc-362638
25 mg
$195.00
(0)

CruzQuench™ 2 succinimidyl ester is a sophisticated quencher characterized by its reactive succinimidyl moiety, which engages in selective covalent bonding with nucleophiles. This compound exhibits a high degree of specificity in molecular interactions, enabling targeted quenching of fluorescence. Its unique reactivity profile allows for rapid formation of stable adducts, effectively minimizing background noise in fluorescence assays and enhancing signal clarity through efficient energy transfer mechanisms.

CruzQuench™ 3 acid

sc-362641
100 mg
$195.00
(0)

CruzQuench™ 3 acid is a highly reactive quencher distinguished by its unique acid halide structure, which facilitates rapid acylation reactions with nucleophiles. This compound showcases exceptional reaction kinetics, allowing for swift quenching of excited states through efficient energy transfer. Its distinctive molecular interactions promote the formation of transient intermediates, leading to enhanced quenching efficiency and reduced fluorescence background, making it ideal for precise analytical applications.

CruzQuench™ 3 amine

sc-362642
5 mg
$195.00
(0)

CruzQuench™ 3 amine is a specialized quencher characterized by its unique amine functionality, which enables effective interaction with various reactive species. This compound exhibits remarkable selectivity in quenching processes, facilitating the stabilization of excited states through specific hydrogen bonding and electron donation mechanisms. Its distinct kinetic profile allows for rapid deactivation of excited states, minimizing unwanted side reactions and enhancing overall quenching performance in diverse chemical environments.

CruzQuench™ 3 CPG 1000 Å

sc-362643
100 mg
$195.00
(0)

CruzQuench™ 3 CPG 1000 Å is a sophisticated quencher distinguished by its unique structural features that promote effective energy transfer and molecular interactions. This compound exhibits a high affinity for excited state species, utilizing specific van der Waals forces and dipole interactions to enhance quenching efficiency. Its tailored surface area and porosity facilitate rapid diffusion, optimizing reaction kinetics and ensuring precise control over energy dissipation in complex chemical systems.

CruzQuench™ 3 CPG 500 Å

sc-362644
100 mg
$195.00
(0)

CruzQuench™ 3 CPG 500 Å is an advanced quencher characterized by its exceptional ability to modulate fluorescence through selective energy transfer mechanisms. Its unique molecular architecture allows for enhanced interactions with excited states, leveraging hydrogen bonding and π-π stacking to achieve superior quenching performance. The compound's finely tuned pore structure promotes efficient mass transport, enabling rapid equilibration and precise control over photophysical processes in diverse environments.

CruzQuench™ 3 phosphoramidite

sc-362646
100 µmol
$195.00
(0)

CruzQuench™ 3 phosphoramidite stands out as a sophisticated quencher, exhibiting remarkable efficiency in fluorescence suppression through intricate molecular interactions. Its design facilitates strong dipole-dipole interactions and robust stacking with adjacent chromophores, leading to effective energy dissipation. The compound's unique electronic properties enhance its reactivity, allowing for rapid quenching kinetics and precise modulation of luminescent signals in various experimental setups.

CruzQuench™ 3 succinimidyl ester

sc-362647
25 mg
$195.00
(0)

CruzQuench™ 3 succinimidyl ester serves as an advanced quencher, characterized by its ability to form stable covalent bonds with amine-containing molecules. This reactivity enables selective targeting and efficient energy transfer, minimizing background fluorescence. Its unique structure promotes effective steric hindrance, which enhances quenching efficiency. The compound's distinct electronic configuration allows for tailored interactions, optimizing quenching pathways and improving signal clarity in diverse applications.

CruzQuench™ 4 acid

sc-362648
25 mg
$295.00
(0)

CruzQuench™ 4 acid is a specialized quencher that exhibits remarkable reactivity with nucleophiles, facilitating rapid and selective interactions. Its unique structural features enable it to engage in specific molecular pathways, enhancing quenching efficiency through dynamic resonance stabilization. The compound's distinctive electronic properties allow for fine-tuning of reaction kinetics, promoting effective energy dissipation. This results in improved signal resolution and minimized interference in various experimental contexts.

CruzQuench 4 alkyne

sc-362649
1 mg
$195.00
(0)

CruzQuench™ 4 alkyne is an innovative quencher characterized by its exceptional ability to engage in π-π stacking interactions, which enhances its quenching efficiency. Its unique steric configuration allows for selective binding to excited states, promoting rapid energy transfer processes. The compound's distinct electronic characteristics facilitate a tailored response to varying environmental conditions, optimizing reaction kinetics and ensuring precise control over fluorescence dynamics in diverse applications.