PPP1R12C Activators
Protein Phosphatase 1 Regulatory Subunit 12C (PPP1R12C), also known as Myosin Phosphatase Target Subunit 3 (MYPT3), is a protein that in humans is encoded by the PPP1R12C gene. This protein is part of the protein phosphatase 1 (PP1) regulatory subunits, which are essential for PP1 function.PP1 is a major serine/threonine phosphatase in eukaryotic cells, regulating a variety of cellular processes by dephosphorylating numerous substrates. The specificity of PP1 is determined by its regulatory subunits, which target PP1 to specific locations and substrates within the cell.
PPP1R12C is primarily expressed in the brain and heart. It has a conserved PP1 binding motif at its C-terminus, suggesting its role in targeting PP1 to specific substrates. Additionally, PPP1R12C contains a kinase-inducible domain interacting (KIX) domain, which is known to mediate protein-protein interactions in various signaling pathways.Although the precise biological functions of PPP1R12C are not fully understood, its association with PP1 suggests a role in a wide range of cellular processes, including protein synthesis, cell division, glycogen metabolism, muscle contraction, and neuronal signaling.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $163.00 $800.00 | 59 | |
Another inhibitor of protein phosphatases, potentially influencing PPP1R12C activity indirectly. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, potentially influencing signaling pathways associated with PPP1R12C. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
As a secondary messenger, it can modulate various signaling pathways, potentially affecting PPP1R12C. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A protein kinase inhibitor, could indirectly affect PPP1R12C by altering kinase activity. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $105.00 $242.00 | 36 | |
Inhibits protein kinase C, potentially affecting PPP1R12C indirectly. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor, known to affect cell growth and signaling, potentially influencing PPP1R12C. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
A key regulator of glucose metabolism, could indirectly affect PPP1R12C through signaling pathways. | ||||||