POMGnT1 Antibodies

Santa Cruz Biotechnology features a diverse variety of POMGnT1 monoclonal antibodies for research focused on understanding POMGnT1 protein function. Multiple detection methods are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).POMGnT1, or protein O-linked mannose N-acetylglucosaminyltransferase 1, is crucial for the proper glycosylation of alpha-dystroglycan, a protein that plays a significant role in muscle function and cell adhesion. Mutations in the POMGnT1 gene are associated with congenital muscular dystrophies, highlighting its importance in muscle integrity and development. Understanding POMGnT1 function is essential for elucidating the molecular mechanisms underlying muscular disorders. Research has shown that POMGnT1 activity directly impacts muscle cell stability and organization. Recent studies have revealed new insights into how POMGnT1 modifications affect cellular signaling pathways. Ongoing investigations continue to uncover novel aspects of POMGnT1's role in muscle development and maintenance. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of muscular dystrophies and potential therapeutic approaches.