Polycyclic aromatic hydrocarbon inhibitors belong to a distinct chemical class characterized by their ability to interfere with the activity of polycyclic aromatic hydrocarbons (PAHs). These inhibitors are compounds that exhibit a specific structural configuration, typically comprising multiple interconnected aromatic rings. The structural arrangement of these rings grants them the capability to disrupt the functions of PAHs through various mechanisms. PAHs are a group of organic molecules composed of fused benzene rings, often found in environmental sources such as combustion products, industrial emissions, and even some natural sources like volcanic eruptions.
They are known for their to interact with cellular processes and genetic material, sometimes leading to harmful effects on organisms and the environment. Polycyclic aromatic hydrocarbon inhibitors act by binding to PAHs or modulating their chemical reactivity, thereby altering their biological interactions and adverse effects. The inhibition of PAHs by these compounds represents a significant area of research, as scientists aim to develop strategies to mitigate the harmful impacts of PAHs.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Fluoranthene | 206-44-0 | sc-239999 | 5 g | $218.00 | ||
Inhibits cytochrome P450 enzymes involved in PAH metabolism, reducing activation and promoting excretion. | ||||||
Benzo[a]pyrene | 50-32-8 | sc-257130 | 1 g | $612.00 | 4 | |
Metabolized by enzymes into reactive intermediates that can form DNA adducts, leading to genotoxicity. Inhibiting its activation prevents DNA damage. | ||||||
Dibenz[a,h]anthracene | 53-70-3 | sc-257317 | 100 mg | $255.00 | ||
Blocks the AhR (aryl hydrocarbon receptor) pathway, which regulates xenobiotic metabolism, reducing PAH-mediated toxicity. | ||||||
Benzo[b]fluoranthene | 205-99-2 | sc-239303 | 25 mg | $57.00 | ||
Inhibits CYP1A1 enzyme, which activates PAHs, thereby reducing the formation of toxic metabolites. | ||||||
Chrysene | 218-01-9 | sc-239555 | 100 mg | $125.00 | ||
Modulates Phase I and Phase II enzymes, disrupting PAH activation and promoting their detoxification and elimination. | ||||||
Indeno[1,2,3-cd]pyrene | 193-39-5 | sc-257601 | 10 mg | $204.00 | ||
Blocks the AhR signaling pathway, which controls xenobiotic metabolism, thereby reducing PAH-induced cellular damage. | ||||||
Benzo[e]pyrene | 192-97-2 | sc-257135 | 25 mg | $541.00 | ||
Interferes with key enzymes involved in PAH metabolism, leading to a reduction in toxic metabolite formation. | ||||||
Benzo[ghi]perylene | 191-24-2 | sc-503388 | 100 mg | $430.00 | ||
Disrupts AhR-regulated pathways, lowering the activation of PAHs and decreasing their toxic effects. | ||||||
Coronene | 191-07-1 | sc-252636 sc-252636A | 100 mg 500 mg | $86.00 $280.00 | ||
Interferes with PAH binding to DNA and other cellular components, reducing genotoxicity and mutagenicity. | ||||||