Date published: 2026-3-17

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POLA Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of POLA Antibodies for research focused on understanding DNA polymerase alpha (POLA). POLA Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). DNA polymerase alpha (POLA) plays a critical role in DNA replication and repair, making it essential for maintaining genomic stability. POLA function is vital in cellular processes, and its dysregulation can lead to various diseases, including cancer. Understanding the mechanisms involving DNA polymerase alpha advances therapeutic strategies and improves disease outcomes. Researchers worldwide utilize POLA monoclonal antibodies to investigate DNA replication pathways and their impact on cellular health. POLA research contributes significantly to understanding cell cycle regulation and DNA damage response mechanisms. Ongoing studies of DNA polymerase alpha continue to reveal new insights into cancer development and potential treatment approaches. Santa Cruz Biotechnology monoclonal antibodies for POLA support researchers in advancing scientific knowledge and developing innovative therapeutic strategies.

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POLA Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

POLA2 Antibody (D-2)

sc-398255mouse IgG1 κ121-420 (h)WB, IP, IF, ELISAm, r, h
2
(2)

POLA2 Antibody (2759C3a)

sc-81568mouse IgG2bN-Terminal (h)WB, IPh

new

(1)

POLA CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

POLA2 HDR Plasmid (h)

sc-407688-HDRhHomology Directed RepairPuromycin0
(0)

POLA siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

POLA2 siRNA (h)

sc-96906hGene SilencingN/A0
(0)

POLA2 shRNA Plasmid (h)

sc-96906-SHhGene SilencingPuromycin0
(0)

POLA2 shRNA (h) Lentiviral Particles

sc-96906-VhGene SilencingPuromycin0
(0)

POLA2 siRNA (m)

sc-152369mGene SilencingN/A0
(0)

POLA2 shRNA Plasmid (m)

sc-152369-SHmGene SilencingPuromycin0
(0)

POLA2 shRNA (m) Lentiviral Particles

sc-152369-VmGene SilencingPuromycin0
(0)