Date published: 2026-2-3

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Podocan Activators

Podocan Activators represent a class of chemicals specifically characterized by their ability to induce the expression of the protein Podocan. Podocan, a member of the small leucine-rich proteoglycan family, plays a pivotal role in the structure and function of the extracellular matrix and is implicated in various biological processes. Podocan Activators, therefore, are thought to interact with cellular mechanisms at the genetic or epigenetic level to enhance the transcription or translation of the Podocan gene. The mechanisms by which these activators function are diverse, reflecting the complexity of gene regulation. Some may bind to receptors or transcription factors, triggering a cascade of intracellular signaling that culminates in the upregulation of Podocan. Others might act by modifying the epigenetic landscape around the Podocan gene, making it more accessible for transcriptional machinery. These chemicals can range from small organic molecules to larger biochemical compounds, each with distinct properties and modes of action that enable them to influence Podocan expression.

The significance of Podocan Activators lies in their role in modulating the cellular and molecular environment where Podocan functions. By influencing Podocan levels, these activators can potentially affect the structure and dynamics of the extracellular matrix, impacting cell adhesion, migration, and signaling. This impact is crucial in understanding the complex interplay of cellular components in various physiological contexts. Moreover, the study of Podocan Activators contributes to the broader understanding of gene regulation, offering insights into the intricate network of interactions that govern protein expression. It's important to recognize that the categorization of these chemicals as Podocan Activators is based on their primary function of influencing Podocan expression; however, like many biochemical agents, they may have secondary actions or effects on other cellular processes. The exploration and characterization of Podocan Activators are thus not only relevant to the field of molecular biology and biochemistry but also contribute to the expanding knowledge of cellular dynamics and protein functions.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid could potentially upregulate Podocan expression through activation of retinoic acid receptors, leading to increased transcription of target genes including Podocan.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$63.00
$182.00
8
(1)

Estradiol might specifically upregulate Podocan expression by binding to estrogen receptors and activating estrogen-responsive elements in the Podocan gene promoter.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin could enhance Podocan expression by activating adenylate cyclase, increasing cAMP, and subsequently promoting the transcription of cAMP-responsive genes like Podocan.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium butyrate, as a histone deacetylase inhibitor, could upregulate Podocan expression by increasing chromatin accessibility for transcription factors at the Podocan gene locus.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol might promote Podocan expression through activation of sirtuin pathways, leading to changes in gene expression patterns, including the upregulation of Podocan.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin could enhance Podocan expression by inhibiting NF-κB, leading to the upregulation of genes negatively regulated by NF-κB, which might include Podocan.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$156.00
$1248.00
$12508.00
82
(1)

Insulin might upregulate Podocan expression in insulin-responsive tissues by activating insulin signaling pathways, which can lead to increased transcription of certain genes.

Metformin-d6, Hydrochloride

1185166-01-1sc-218701
sc-218701A
sc-218701B
1 mg
5 mg
10 mg
$292.00
$822.00
$1540.00
1
(1)

Metformin could potentially upregulate Podocan expression via AMPK activation, influencing cellular metabolism and gene transcription patterns.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$71.00
$163.00
$296.00
2
(1)

Cholecalciferol might specifically enhance Podocan expression through its active metabolite, calcitriol, which binds to the vitamin D receptor and activates transcription of vitamin D-responsive genes.

Hydrocortisone

50-23-7sc-300810
5 g
$102.00
6
(1)

Hydrocortisone might upregulate Podocan expression by activating glucocorticoid receptors, leading to changes in gene transcription including potential enhancement of Podocan.