PLEKHG6 Activators
Compounds like Rhosin, Y-27632, NSC23766, and ML141, which target Rho GTPases and their downstream effectors, can modulate cytoskeletal dynamics and cell migration, processes in which PLEKHG6 is likely involved. By altering the activity of key molecules in these pathways, these compounds might indirectly enhance the functional role of PLEKHG6 in cellular reorganization and movement.
LY294002 and PD98059, targeting the PI3K/Akt and MAPK/ERK pathways respectively, could influence PLEKHG6's function in cell survival and proliferation. Forskolin, by increasing cAMP levels, might also affect PLEKHG6-mediated signaling pathways, especially those related to cell motility. Wiskostatin, CK-666, and Jasplakinolide, by modulating the dynamics of the actin cytoskeleton, could affect PLEKHG6's role in actin filament organization and cell shape. Moreover, Blebbistatin and ML7, which inhibit myosin II and MLCK, could impact processes of cell motility and contraction where PLEKHG6 might be functionally active.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor, could affect PI3K/Akt signaling pathways, potentially influencing PLEKHG6's role in cell survival and migration. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
Inhibits the MAPK/ERK pathway, which could indirectly impact PLEKHG6's function in signaling pathways related to cell proliferation and migration. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels. This might influence PLEKHG6-mediated signaling pathways, especially those related to cell motility. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $49.00 $124.00 $441.00 $828.00 | 4 | |
Inhibits N-WASP, a regulator of actin polymerization. This could affect PLEKHG6's role in actin cytoskeleton reorganization. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $321.00 $1040.00 | 5 | |
Inhibits the Arp2/3 complex, potentially impacting PLEKHG6's involvement in actin filament branching and cell movement. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Stabilizes actin filaments, potentially influencing PLEKHG6's function in actin dynamics and cell morphology. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $72.00 $265.00 $495.00 $968.00 | ||
Inhibits myosin II, affecting myosin-driven cell motility processes where PLEKHG6 might play a role. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
Inhibits myosin light chain kinase (MLCK), potentially affecting PLEKHG6's involvement in cellular processes driven by actomyosin contraction. | ||||||