Date published: 2025-9-5

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Phthaleins

Santa Cruz Biotechnology now offers a broad range of phthaleins for use in various applications. Phthaleins are a group of organic compounds commonly known for their vibrant colors, which make them valuable as pH indicators in chemical analysis and laboratory experiments. These compounds are synthesized through the reaction of phthalic anhydride with phenols, resulting in a class of molecules characterized by their distinctive structural frameworks. In scientific research, phthaleins are crucial for studying chemical equilibria, reaction mechanisms, and the properties of various substances under different pH conditions. Beyond their role as indicators, phthaleins also serve as intermediates in the synthesis of dyes, pigments, and polymers, making them indispensable in materials science and industrial chemistry. Their unique optical properties allow researchers to visualize and quantify chemical processes, thus providing a deeper understanding of molecular interactions and behaviors. The versatility of phthaleins extends to fields such as environmental science, where they are used to detect pollutants and assess water quality. By leveraging the distinctive features of phthaleins, scientists can innovate and improve analytical techniques, contributing to advancements in both basic and applied sciences. View detailed information on our available phthaleins by clicking on the product name.

Items 1 to 10 of 16 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Phenol Red

143-74-8sc-203752
sc-203752A
sc-203752B
5 g
25 g
250 g
$36.00
$85.00
$311.00
3
(1)

Phenol Red is a pH indicator characterized by its vibrant color change in response to varying acidity levels. Its unique structure allows for strong hydrogen bonding interactions, influencing its behavior in aqueous solutions. The compound exhibits distinct reaction kinetics, transitioning from yellow to red as pH increases, which is attributed to its tautomeric forms. Additionally, its solubility in water and organic solvents enhances its versatility in various chemical environments.

Rhodamine B isothiocyanate

36877-69-7sc-219968
sc-219968A
100 mg
500 mg
$229.00
$715.00
5
(1)

Rhodamine B isothiocyanate is a fluorescent dye known for its robust photostability and high quantum yield. Its unique isothiocyanate group facilitates covalent bonding with nucleophiles, enhancing its reactivity in labeling applications. The compound exhibits strong intermolecular interactions, contributing to its intense fluorescence. Additionally, its solubility in polar solvents allows for effective incorporation into diverse chemical systems, making it a valuable tool in various analytical techniques.

Bromosulfalein

71-67-0sc-206045
sc-206045A
5 g
25 g
$122.00
$362.00
2
(1)

Bromosulfalein is a synthetic dye characterized by its distinct chromophoric structure, which enables it to exhibit a pronounced color change in response to pH variations. This compound undergoes specific protonation and deprotonation reactions, influencing its spectral properties. Its unique interactions with metal ions can lead to complex formation, altering its optical characteristics. Additionally, Bromosulfalein's solubility in organic solvents enhances its versatility in various chemical environments.

Bromocresol Green

76-60-8sc-206048
25 g
$158.00
(0)

Bromocresol Green is a synthetic pH indicator known for its unique structural features that facilitate a notable color transition between acidic and basic conditions. Its behavior is governed by protonation dynamics, which affect its electronic configuration and absorption spectrum. The compound exhibits distinct interactions with various ions, leading to potential shifts in its colorimetric response. Furthermore, its solubility in both aqueous and organic media allows for diverse applications in analytical chemistry.

3′,3″,5′,5″-Tetraiodophenolsulfonephthalein

4430-24-4sc-206023B
sc-206023
1 g
5 g
$153.00
$408.00
(1)

3′,3′′,5′,5′′-Tetraiodophenolsulfonephthalein is a synthetic compound characterized by its intricate molecular structure, which enables it to exhibit distinct chromatic shifts in response to pH changes. The presence of multiple iodine atoms enhances its electron-withdrawing properties, influencing its reactivity and stability in various environments. This compound's unique interactions with metal ions can lead to complex formation, altering its optical properties and expanding its utility in diverse chemical analyses.

Bromothymol Blue

76-59-5sc-206047
sc-206047A
5 g
25 g
$37.00
$130.00
(0)

Bromothymol Blue is a pH indicator known for its striking color transition from yellow to blue as pH shifts from acidic to neutral and alkaline conditions. Its unique structure allows for effective protonation and deprotonation, facilitating rapid equilibrium shifts. The compound's hydrophobic regions enhance its solubility in organic solvents, while its aromatic rings contribute to strong π-π stacking interactions, influencing its optical characteristics and reactivity in various chemical environments.

Thymol Blue

76-61-9sc-206049
sc-206049A
5 g
25 g
$31.00
$92.00
2
(0)

Thymol Blue is a versatile pH indicator that exhibits a distinct color change from yellow to blue across a specific pH range, reflecting its dual acid-base behavior. Its molecular structure features a sulfonic acid group, which enhances solubility in aqueous solutions. The compound's ability to undergo tautomerization allows for dynamic shifts in its electronic configuration, affecting its light absorption properties. Additionally, its strong hydrogen bonding capabilities contribute to its stability in various chemical contexts.

Phenolphthalein

77-09-8sc-206050
sc-206050A
100 g
500 g
$39.00
$134.00
1
(1)

Phenolphthalein is a notable pH indicator characterized by its striking color transition from colorless to pink as pH increases, highlighting its sensitivity to hydrogen ion concentration. Its unique structure allows for intramolecular hydrogen bonding, which stabilizes its anionic form in alkaline conditions. The compound's electron-rich aromatic rings facilitate resonance, enhancing its light absorption properties. This behavior underscores its role in acid-base titrations, where reaction kinetics are influenced by the rapid equilibrium between its protonated and deprotonated states.

Pyrocatechol Violet

115-41-3sc-215764
sc-215764A
5 g
10 g
$56.00
$97.00
(0)

Pyrocatechol Violet is a distinctive pH indicator known for its vivid color change from yellow to violet in response to pH variations. Its unique molecular structure features multiple hydroxyl groups that engage in strong intermolecular hydrogen bonding, influencing its solubility and stability in various environments. The compound exhibits notable electron delocalization across its aromatic system, which enhances its light absorption and alters its spectral properties, making it effective in detecting subtle pH shifts.

m-Cresol Purple

2303-01-7sc-215274
sc-215274A
sc-215274B
1 g
5 g
10 g
$20.00
$52.00
$92.00
1
(0)

m-Cresol Purple is a notable pH indicator characterized by its striking color transition from yellow to purple as pH levels fluctuate. Its unique structure, featuring a central phenolic ring, allows for effective protonation and deprotonation, facilitating rapid response to acidity changes. The compound's distinct electron distribution enhances its chromatic properties, while its hydrophobic regions contribute to selective solubility, making it particularly responsive in diverse chemical environments.