Date published: 2026-4-15

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Phosphatases and Phosphatase Activators & Inhibitors

Santa Cruz Biotechnology now offers a broad range of phosphatases and phosphatase activators and inhibitors for use in various applications. Phosphatases are enzymes that remove phosphate groups from proteins, nucleotides, and other molecules, playing a critical role in regulating cellular processes such as signal transduction, metabolism, and cell cycle progression. Researchers utilize phosphatases to study the dynamic balance of phosphorylation and dephosphorylation that controls protein function and cellular activities. Phosphatase activators and inhibitors are essential tools for investigating the regulation and function of these enzymes. By selectively modulating phosphatase activity, scientists can dissect signaling pathways, explore the mechanisms of enzyme regulation, and understand the physiological and pathological roles of phosphorylation. These compounds are widely used in research areas such as cancer biology, neurobiology, and metabolic studies, where aberrant phosphorylation is often implicated. By providing a comprehensive selection of high-quality phosphatases, activators, and inhibitors, Santa Cruz Biotechnology supports advanced research in biochemistry, molecular biology, and cell biology. These products enable precise and reproducible experiments, driving advancements in our understanding of cellular signaling and regulation. View detailed information on our available phosphatases and phosphatase activators and inhibitors by clicking on the product name.

Items 81 to 84 of 84 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PTP1B Substrate

sc-3126
0.5 mg
$97.00
3
(0)

PTP1B Substrate is a critical player in cellular signaling, acting as a specific target for protein tyrosine phosphatases. It facilitates the dephosphorylation of tyrosine residues, influencing various signaling cascades. The substrate's unique structural motifs allow for selective interactions with PTP1B, enhancing reaction kinetics. Its role in modulating protein interactions and cellular responses underscores its significance in maintaining cellular homeostasis and regulating metabolic pathways.

Alkaline Phosphatase (AP)

9001-78-9sc-3716
sc-3716A
1 mg
5 mg
$63.00
$218.00
2
(0)

Alkaline Phosphatase (AP) is a key enzyme that catalyzes the hydrolysis of phosphate esters, playing a crucial role in various biological processes. It operates optimally in alkaline conditions, showcasing unique substrate specificity and reaction kinetics. AP's activity is influenced by metal ions, which can enhance its catalytic efficiency. The enzyme's ability to dephosphorylate molecules impacts metabolic pathways, cellular signaling, and energy transfer, highlighting its importance in physiological regulation.

Saccharin Sodium Salt

128-44-9sc-296367
sc-296367A
100 g
500 g
$64.00
$142.00
(1)

Saccharin Sodium Salt acts as a phosphatase inhibitor, characterized by its unique ability to interact with the active site of phosphatases, leading to altered enzymatic activity. Its structural features facilitate non-competitive inhibition, impacting the rate of dephosphorylation. This compound can influence various signaling cascades by modulating phosphate group transfer, providing insights into cellular regulation and metabolic pathways. Its distinct interactions make it a valuable tool for studying phosphatase dynamics.

RWJ-60475

204130-08-5sc-222266
sc-222266A
5 mg
25 mg
$153.00
$663.00
(0)

RWJ-60475 is a selective inhibitor of phosphatases, exhibiting unique binding affinity that disrupts the enzyme-substrate interaction. Its distinct molecular structure allows for competitive inhibition, altering the kinetics of dephosphorylation reactions. By stabilizing the transition state, RWJ-60475 modulates the activity of specific phosphatases, influencing downstream signaling pathways. This compound's ability to selectively target phosphatases highlights its potential in dissecting complex cellular mechanisms.