PFKL Inhibitors
PFKL inhibitors belong to a specific chemical class of compounds that have been studied and designed to selectively target and inhibit the activity of PFKL, also known as Phosphofructokinase liver type. PFKL is an isoform of phosphofructokinase, an enzyme that plays a key role in regulating glycolysis, the metabolic pathway responsible for breaking down glucose into pyruvate to produce energy. Inhibition of PFKL aims to block its enzymatic function, which can alter the glycolytic pathway and affect cellular energy metabolism.
The chemical structures of PFKL inhibitors can vary, and researchers have explored various small-molecule compounds that may interact with PFKL and modulate its activity. Continued research in this chemical class may provide valuable insights into the regulation of glucose metabolism and energy production in various biological contexts. Understanding the mechanisms of PFKL inhibition could shed light on its role in cellular physiology and may have implications in metabolic regulation and energy homeostasis.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
9-Aminoacridine free base | 90-45-9 | sc-291761A sc-291761 sc-291761B sc-291761C | 250 mg 1 g 5 g 10 g | $32.00 $80.00 $272.00 $501.00 | ||
9-AA is known to inhibit PFKL activity and glycolysis, which has been explored in the context of cancer cell metabolism. | ||||||
Oxamic acid | 471-47-6 | sc-250620 | 25 g | $148.00 | ||
An organic compound that can inhibit PFKL and other enzymes involved in glycolysis, affecting glucose metabolism. | ||||||
Sodium dichloroacetate | 2156-56-1 | sc-203275 sc-203275A | 10 g 50 g | $55.00 $209.00 | 6 | |
Although primarily studied as a pyruvate dehydrogenase kinase inhibitor, DCA can also influence PFKL activity and glycolytic flux. | ||||||