Date published: 2025-10-26

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PEN-2 Antibodies

Santa Cruz Biotechnology delivers a wide array of PEN-2 monoclonal antibodies for research in understanding PEN-2's role in cellular processes. The monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PEN-2, or presenilin enhancer 2, functions as a key component of the gamma-secretase complex, participating in the proteolytic processing of amyloid precursor protein (APP). The processing of APP significantly impacts the production of amyloid-beta peptides, making it particularly relevant to Alzheimer's disease research. Understanding PEN-2's function provides crucial insights into the mechanisms of neurodegenerative diseases and aids in developing potential therapeutic strategies. Researchers can investigate cellular pathways and molecular mechanisms through precise detection and analysis of PEN-2. Advanced research techniques enable detailed examination of PEN-2's involvement in various biological processes. Comprehensive studies of PEN-2 contribute to expanding knowledge in neurobiology and related fields. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of neurodegenerative diseases and potential therapeutic approaches.

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PEN-2 Antibodies

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PEN-2 Antibody (1C12-G5)

sc-293392mouse IgG1 κ1-101 (h)WB, IP, ELISAm, r, h
1
(1)

PEN-2 CRISPR Knockout, HDR and Double Nickase Plasmids

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PEN-2 CRISPR/Cas9 KO Plasmid (h)

sc-416265hGene KnockoutGFP0
(0)

PEN-2 HDR Plasmid (h)

sc-416265-HDRhHomology Directed RepairPuromycin0
(0)

PEN-2 Double Nickase Plasmid (h)

sc-416265-NIChGene KnockoutPuromycin0
(0)

PEN-2 Double Nickase Plasmid (h2)

sc-416265-NIC-2hGene KnockoutPuromycin0
(0)

PEN-2 CRISPR/Cas9 KO Plasmid (m)

sc-425961mGene KnockoutGFP0
(0)

PEN-2 HDR Plasmid (m)

sc-425961-HDRmHomology Directed RepairPuromycin0
(0)

PEN-2 Double Nickase Plasmid (m)

sc-425961-NICmGene KnockoutPuromycin0
(0)

PEN-2 Double Nickase Plasmid (m2)

sc-425961-NIC-2mGene KnockoutPuromycin0
(0)

PEN-2 CRISPR Activation Products

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PEN-2 CRISPR Activation Plasmid (h)

sc-416265-ACThGene ActivationPuro, Blast, Hygro0
(0)

PEN-2 CRISPR Activation Plasmid (h2)

sc-416265-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PEN-2 Lentiviral Activation Particles (h)

sc-416265-LAChGene ActivationPuro, Blast, Hygro0
(0)

PEN-2 Lentiviral Activation Particles (h2)

sc-416265-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PEN-2 CRISPR Activation Plasmid (m)

sc-425961-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PEN-2 CRISPR Activation Plasmid (m2)

sc-425961-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PEN-2 Lentiviral Activation Particles (m)

sc-425961-LACmGene ActivationPuro, Blast, Hygro0
(0)

PEN-2 Lentiviral Activation Particles (m2)

sc-425961-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PEN-2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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PEN-2 siRNA (h)

sc-45986hGene SilencingN/A
1
(0)

PEN-2 shRNA Plasmid (h)

sc-45986-SHhGene SilencingPuromycin
1
(0)

PEN-2 shRNA (h) Lentiviral Particles

sc-45986-VhGene SilencingPuromycin
1
(0)

PEN-2 siRNA (m)

sc-45987mGene SilencingN/A0
(0)

PEN-2 shRNA Plasmid (m)

sc-45987-SHmGene SilencingPuromycin0
(0)

PEN-2 shRNA (m) Lentiviral Particles

sc-45987-VmGene SilencingPuromycin0
(0)