PDGF Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Suramin sodium | 129-46-4 | sc-507209 sc-507209F sc-507209A sc-507209B sc-507209C sc-507209D sc-507209E | 50 mg 100 mg 250 mg 1 g 10 g 25 g 50 g | $152.00 $214.00 $728.00 $2601.00 $10965.00 $21838.00 $41096.00 | 5 | |
Suramin sodium exhibits a distinctive ability to interact with various biological macromolecules, primarily through electrostatic and hydrophobic interactions. Its large, multi-ring structure allows for extensive surface area engagement, facilitating binding to proteins and nucleic acids. This compound can disrupt specific protein-protein interactions, influencing cellular signaling pathways. Additionally, its solubility characteristics enable diverse reaction kinetics, impacting its behavior in complex biological environments. | ||||||
4-Chloro-6,7-bis-(2-methoxy-ethoxy)-quinazoline | 183322-18-1 | sc-357724 sc-357724A | 100 mg 250 mg | $131.00 $262.00 | ||
4-Chloro-6,7-bis-(2-methoxy-ethoxy)-quinazoline demonstrates unique molecular interactions through its selective binding affinity for PDGF receptors. The compound's structural configuration allows for precise alignment within the receptor's active site, enhancing its inhibitory effects on downstream signaling pathways. Its distinct electronic properties contribute to favorable reaction kinetics, promoting stability in various environments. This compound's hydrophobic regions facilitate interactions with lipid membranes, influencing cellular uptake and distribution. | ||||||
Sennoside B | 128-57-4 | sc-258154 sc-258154A | 25 mg 500 mg | $159.00 $942.00 | ||
Sennoside B exhibits intriguing molecular behavior as a potent PDGF modulator, characterized by its ability to engage in specific hydrogen bonding with receptor sites. This interaction initiates a cascade of intracellular signaling, influencing cellular proliferation and migration. The compound's unique stereochemistry enhances its affinity for PDGF receptors, while its solubility profile allows for effective diffusion across cellular membranes, impacting bioavailability and receptor engagement dynamics. | ||||||
Nilvadipine | 75530-68-6 | sc-215567 | 50 mg | $177.00 | 1 | |
Nilvadipine demonstrates unique molecular interactions as a PDGF modulator, primarily through its selective binding to receptor sites that triggers downstream signaling pathways. Its distinct lipophilic characteristics facilitate membrane permeability, enhancing its interaction kinetics with target proteins. The compound's conformational flexibility allows for optimal alignment with PDGF receptors, promoting effective signal transduction and influencing cellular behavior in a nuanced manner. | ||||||
4-Dechloro-2-chloro-regorafenib | sc-500702 | 10 mg | $430.00 | |||
4-Dechloro-2-chloro-regorafenib exhibits distinctive interactions as a PDGF antagonist, characterized by its ability to disrupt receptor dimerization. This compound's unique steric configuration enables it to effectively block the phosphorylation of downstream signaling molecules, altering cellular responses. Its hydrophobic regions enhance affinity for lipid membranes, influencing its distribution and interaction dynamics within cellular environments, ultimately affecting the modulation of growth factor signaling pathways. | ||||||