Date published: 2025-10-6

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PBGS Antibodies

Santa Cruz Biotechnology features a diverse variety of PBGS monoclonal antibodies for studying porphobilinogen synthase (PBGS). PBGS Antibodies are available for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Porphobilinogen synthase plays a crucial role in the heme biosynthesis pathway, catalyzing the condensation of two molecules of 5-aminolevulinic acid to form porphobilinogen. PBGS is essential for the production of heme, which is vital for various biological processes, including oxygen transport and electron transfer in cellular respiration. Understanding PBGS function and regulation provides insights into metabolic disorders related to heme synthesis. Research into PBGS activity helps advance knowledge about disorders affecting heme production and metabolism. Investigating PBGS expression patterns reveals important information about cellular energy processes and oxygen transport mechanisms. PBGS research contributes to understanding both normal physiological processes and disease states. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of heme biosynthesis and its impact on human health.

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PBGS Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PBGS Antibody (A-7)

sc-271585mouse IgG1 κ1-300 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(2)

PBGS Antibody (E-10)

sc-398308mouse IgG1 κ142-159 (h)WB, IP, IF, ELISAm, r, h

new

(1)

PBGS Antibody (G-9)

sc-365095mouse IgG2a κ1-300 (h)WB, IP, IF, ELISAm, r, h

new

(2)

PBGS CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PBGS CRISPR/Cas9 KO Plasmid (h)

sc-407260hGene KnockoutGFP0
(0)

PBGS HDR Plasmid (h)

sc-407260-HDRhHomology Directed RepairPuromycin0
(0)

PBGS Double Nickase Plasmid (h)

sc-407260-NIChGene KnockoutPuromycin0
(0)

PBGS Double Nickase Plasmid (h2)

sc-407260-NIC-2hGene KnockoutPuromycin0
(0)

PBGS CRISPR/Cas9 KO Plasmid (m)

sc-421488mGene KnockoutGFP0
(0)

PBGS HDR Plasmid (m)

sc-421488-HDRmHomology Directed RepairPuromycin0
(0)

PBGS Double Nickase Plasmid (m)

sc-421488-NICmGene KnockoutPuromycin0
(0)

PBGS Double Nickase Plasmid (m2)

sc-421488-NIC-2mGene KnockoutPuromycin0
(0)

PBGS CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PBGS CRISPR Activation Plasmid (h)

sc-407260-ACThGene ActivationPuro, Blast, Hygro0
(0)

PBGS CRISPR Activation Plasmid (h2)

sc-407260-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PBGS Lentiviral Activation Particles (h)

sc-407260-LAChGene ActivationPuro, Blast, Hygro0
(0)

PBGS Lentiviral Activation Particles (h2)

sc-407260-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PBGS CRISPR Activation Plasmid (m)

sc-421488-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PBGS CRISPR Activation Plasmid (m2)

sc-421488-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PBGS Lentiviral Activation Particles (m)

sc-421488-LACmGene ActivationPuro, Blast, Hygro0
(0)

PBGS Lentiviral Activation Particles (m2)

sc-421488-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PBGS siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PBGS siRNA (h)

sc-61385hGene SilencingN/A
1
(0)

PBGS shRNA Plasmid (h)

sc-61385-SHhGene SilencingPuromycin
1
(0)

PBGS shRNA (h) Lentiviral Particles

sc-61385-VhGene SilencingPuromycin
1
(0)

PBGS siRNA (m)

sc-61386mGene SilencingN/A0
(0)

PBGS shRNA Plasmid (m)

sc-61386-SHmGene SilencingPuromycin0
(0)

PBGS shRNA (m) Lentiviral Particles

sc-61386-VmGene SilencingPuromycin0
(0)