Date published: 2026-4-16

1-800-457-3801

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Patched Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Patched Antibodies for studying the Patched protein, a critical component of the Hedgehog signaling pathway. Patched Antibodies are compatible with multiple research techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The Patched protein plays a vital role in regulating cell growth and differentiation, making it essential for proper embryonic development and tissue homeostasis. Dysregulation of Patched has been implicated in several cancers and developmental disorders, highlighting its significance in both basic and translational research. Understanding Patched protein function and regulation is crucial for developing targeted therapeutic strategies. Researchers worldwide rely on Patched monoclonal antibodies to investigate cellular signaling mechanisms and disease pathways. Advanced research tools enable detailed examination of protein-protein interactions within the Hedgehog pathway. Ongoing studies of Patched continue to reveal new insights into developmental biology and disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies for Patched support researchers in advancing scientific understanding of cellular signaling and disease mechanisms.

SEE ALSO...

Patched Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

patched/PTCH1 Antibody (A-2)

sc-518044mouse IgG2a κ1401-1429 (h)WB, IP, IF, ELISAh
2
(1)

patched/PTCH1 Antibody (3B3)

sc-293416mouse IgG2a κ651-750 (h)WB, IP, ELISAh
5
(0)

patched/PTCH1 Antibody (E-7)

sc-518046mouse IgG11402-1429 (h)WB, IP, IF, ELISAh

new

(1)

patched/PTCH1 Antibody (H-10)

sc-518102mouse IgG1 κ270-296 (h)WB, IP, IF, ELISAm, r, h
2
(1)

Non-Mammalian Patched Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

patched/PTCH1 Antibody (188G11)

sc-23929mouse IgG1 κ1194-1286 (drosophila)WB, IP, IFd
1
(3)

Patched CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

patched/PTCH1 CRISPR/Cas9 KO Plasmid (h)

sc-400457hGene KnockoutGFP0
(0)

patched/PTCH1 Double Nickase Plasmid (h)

sc-400457-NIChGene KnockoutPuromycin0
(0)

patched/PTCH1 Double Nickase Plasmid (h2)

sc-400457-NIC-2hGene KnockoutPuromycin0
(0)

patched/PTCH1 Double Nickase Plasmid (m)

sc-422471-NICmGene KnockoutPuromycin0
(0)

patched/PTCH1 Double Nickase Plasmid (m2)

sc-422471-NIC-2mGene KnockoutPuromycin0
(0)

patched 2 CRISPR/Cas9 KO Plasmid (h)

sc-404866hGene KnockoutGFP0
(0)

Patched CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

patched 2 CRISPR Activation Plasmid (h)

sc-404866-ACThGene ActivationPuro, Blast, Hygro0
(0)

Patched siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

patched/PTCH1 siRNA (h)

sc-36192hGene SilencingN/A
3
(0)

patched/PTCH1 shRNA Plasmid (h)

sc-36192-SHhGene SilencingPuromycin
3
(0)

patched/PTCH1 shRNA (h) Lentiviral Particles

sc-36192-VhGene SilencingPuromycin
3
(0)

patched/PTCH1 siRNA (m)

sc-36191mGene SilencingN/A0
(0)

patched/PTCH1 shRNA Plasmid (m)

sc-36191-SHmGene SilencingPuromycin0
(0)

patched/PTCH1 shRNA (m) Lentiviral Particles

sc-36191-VmGene SilencingPuromycin0
(0)

patched 2 siRNA (h)

sc-40159hGene SilencingN/A0
(0)

patched 2 shRNA Plasmid (h)

sc-40159-SHhGene SilencingPuromycin0
(0)

patched 2 shRNA (h) Lentiviral Particles

sc-40159-VhGene SilencingPuromycin0
(0)

patched 2 siRNA (m)

sc-40160mGene SilencingN/A0
(0)

patched 2 shRNA Plasmid (m)

sc-40160-SHmGene SilencingPuromycin0
(0)

patched 2 shRNA (m) Lentiviral Particles

sc-40160-VmGene SilencingPuromycin0
(0)