Date published: 2026-4-5

1-800-457-3801

SCBT Portrait Logo
Seach Input

PARP-1 Antibodies

Santa Cruz Biotechnology delivers a wide array of PARP-1 monoclonal antibodies for research focused on Poly(ADP-ribose) polymerase 1 (PARP-1) in cellular processes. PARP-1 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PARP-1 functions as a key enzyme in cellular responses to DNA damage, with essential roles in DNA repair, genomic stability, and programmed cell death. Understanding PARP-1 activity provides insights into cellular homeostasis maintenance and reveals important connections to cancer biology, neurodegenerative diseases, and aging processes. Research on PARP-1 continues to advance the development of targeted therapies, particularly in oncology where PARP inhibitors show significant therapeutic potential. Scientists worldwide rely on PARP-1 monoclonal antibodies to uncover new pathways and mechanisms in DNA repair and cell death. Ongoing studies of PARP-1 reveal its expanding roles in cellular regulation and disease progression. PARP-1 research supported by Santa Cruz Biotechnology monoclonal antibodies contributes to breakthrough discoveries that advance therapeutic strategies and scientific understanding.

SEE ALSO...

PARP-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PARP1 Antibody (F-2)

sc-8007mouse IgG2a κ764-1014 (h)WB, IP, IF, IHC(P), ELISAh
890
(93)

PARP1 Antibody (B-10)

sc-74470mouse IgG1 κ1-300 (h)WB, IP, IF, IHC(P), ELISAm, r, h
71
(17)

PARP1 Antibody (D-1)

sc-365315mouse IgG1 κ1-27 (m)WB, IP, IF, ELISAm, r, h
27
(10)

PARP1 Antibody (E-8)

sc-74469mouse IgG1 κ1-300 (h)WB, IP, IF, IHC(P), ELISAm, r, h
24
(8)

PARP1 Antibody (5A5)

sc-56197mouse IgG1(h)WB, IP, IFm, r, h
32
(9)

PARP1 Antibody (42)

sc-136208mouse IgG122-219 (h)WB, IP, IFm, r, h
22
(9)

PARP1 Antibody (194C1439)

sc-56196mouse IgG2bcleavage site 214/215 (h)WB, IPm, r, h
128
(27)

PARP-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PARP1 CRISPR/Cas9 KO Plasmid (h)

sc-400046hGene KnockoutGFP
3
(5)

PARP1 HDR Plasmid (h)

sc-400046-HDRhHomology Directed RepairPuromycin
3
(5)

PARP1 Double Nickase Plasmid (h)

sc-400046-NIChGene KnockoutPuromycin
3
(5)

PARP1 Double Nickase Plasmid (h2)

sc-400046-NIC-2hGene KnockoutPuromycin
3
(5)

PARP1 CRISPR/Cas9 KO Plasmid (m)

sc-419018mGene KnockoutGFP
2
(1)

PARP1 HDR Plasmid (m)

sc-419018-HDRmHomology Directed RepairPuromycin
2
(1)

PARP1 Double Nickase Plasmid (m)

sc-419018-NICmGene KnockoutPuromycin
2
(1)

PARP1 Double Nickase Plasmid (m2)

sc-419018-NIC-2mGene KnockoutPuromycin
2
(1)

PARP-1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PARP1 CRISPR Activation Plasmid (h)

sc-400046-ACThGene ActivationPuro, Blast, Hygro
3
(5)

PARP1 Lentiviral Activation Particles (h)

sc-400046-LAChGene ActivationPuro, Blast, Hygro
3
(5)

PARP1 CRISPR Activation Plasmid (m)

sc-419018-ACTmGene ActivationPuro, Blast, Hygro
2
(1)

PARP-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PARP1 siRNA (h)

sc-29437hGene SilencingN/A
43
(3)

PARP1 shRNA Plasmid (h)

sc-29437-SHhGene SilencingPuromycin
43
(3)

PARP1 shRNA (h) Lentiviral Particles

sc-29437-VhGene SilencingPuromycin
43
(3)

PARP1 siRNA (m)

sc-29438mGene SilencingN/A
9
(0)

PARP1 shRNA Plasmid (m)

sc-29438-SHmGene SilencingPuromycin
9
(0)

PARP1 shRNA (m) Lentiviral Particles

sc-29438-VmGene SilencingPuromycin
9
(0)