p38 Inhibitors
Santa Cruz Biotechnology now offers a broad range of p38 Inhibitors. MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38α, p38β and p38γ, also known as MAPK14, MAPK11 and MAPK12, respectively. p38 Inhibitors offered by Santa Cruz inhibit p38 and, in some cases, other signal transduction and cell proliferation related proteins. View detailed p38 Inhibitor specifications, including p38 Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
Items 11 to 15 of 15 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
TAK 715 | 303162-79-0 | sc-362799 sc-362799A | 10 mg 50 mg | $185.00 $781.00 | ||
TAK 715 is a potent p38 MAPK inhibitor, distinguished by its ability to engage in specific hydrogen bonding and hydrophobic interactions with key residues in the enzyme's active site. This selective binding alters the enzyme's conformation, hindering its catalytic activity. The compound exhibits favorable reaction kinetics, allowing for efficient inhibition, while its unique steric properties enhance its specificity, minimizing off-target effects in complex biological systems. | ||||||
SB 220025 trihydrochloride | 197446-75-6 | sc-253537 | 500 µg | $154.00 | ||
SB 220025 trihydrochloride is a selective inhibitor of p38 MAPK, characterized by its ability to form strong ionic interactions with charged amino acids within the enzyme's active site. This binding promotes a conformational shift that effectively blocks substrate binding. The compound's high solubility in aqueous environments facilitates rapid distribution, while its unique structural features contribute to a distinct pharmacophore that influences its interaction dynamics with the target enzyme. | ||||||
PH-797804 | 586379-66-0 | sc-364579 sc-364579A sc-364579B | 5 mg 50 mg 500 mg | $90.00 $510.00 $2550.00 | ||
PH-797804 is a selective p38 MAPK inhibitor that suppresses its activity and downstream signaling. | ||||||
Losmapimod | 585543-15-3 | sc-489299 sc-489299A | 10 mg 50 mg | $224.00 $809.00 | ||
Losmapimod is a selective inhibitor of p38 MAPK, leading to suppression of its activity and function. | ||||||
SD-169 | 1670-87-7 | sc-200693 sc-200693A | 10 mg 50 mg | $58.00 $166.00 | ||
SD-169 is an ATP-competitive inhibitor of p38 MAPK, suppressing its kinase activity and subsequent signaling events. | ||||||