Date published: 2026-4-5

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P2X3 Antibodies

Santa Cruz Biotechnology offers a broad range of P2X3 monoclonal antibodies for studying the P2X3 receptor, a member of the purinergic receptor family that plays a crucial role in pain signaling and sensory neuron activation. P2X3 monoclonal antibodies are compatible with multiple research techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The P2X3 receptor is primarily expressed in sensory neurons and is involved in the transmission of pain signals, making it a significant target for pain management research. Its activation by ATP can lead to the sensation of pain, highlighting its importance in understanding chronic pain conditions and developing therapeutic interventions. P2X3 receptors have been implicated in various neuropathic pain conditions, including inflammatory pain and migraine. Research has shown that targeting P2X3 receptors may offer promising therapeutic approaches for managing chronic pain disorders. Understanding P2X3 receptor function and distribution is essential for developing new pain management strategies. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing pain signaling research and developing innovative therapeutic solutions for chronic pain conditions.

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P2X3 Antibodies

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P2X3 Antibody (B-5)

sc-390572mouse IgG1 κ338-397 (h)WB, IP, IF, ELISAm, r, h
2
(3)

P2X3 CRISPR Knockout, HDR and Double Nickase Plasmids

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P2X3 Double Nickase Plasmid (m)

sc-432763-NICmGene KnockoutPuromycin0
(0)

P2X3 CRISPR Activation Products

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P2X3 CRISPR Activation Plasmid (h)

sc-402380-ACThGene ActivationPuro, Blast, Hygro0
(0)

P2X3 CRISPR Activation Plasmid (h2)

sc-402380-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

P2X3 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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P2X3 siRNA (h)

sc-42567hGene SilencingN/A0
(0)

P2X3 shRNA Plasmid (h)

sc-42567-SHhGene SilencingPuromycin0
(0)

P2X3 shRNA (h) Lentiviral Particles

sc-42567-VhGene SilencingPuromycin0
(0)

P2X3 siRNA (m)

sc-42568mGene SilencingN/A0
(0)

P2X3 shRNA Plasmid (m)

sc-42568-SHmGene SilencingPuromycin0
(0)

P2X3 shRNA (m) Lentiviral Particles

sc-42568-VmGene SilencingPuromycin0
(0)