OY-TES-1 Activators
OY-TES-1 Activators are a diverse set of chemical compounds that facilitate the enhancement of the functional activity of OY-TES-1 through various specific signaling pathways. The activators such as Forskolin and IBMX work by elevating intracellular cAMP levels or inhibiting its degradation, respectively, ultimately leading to the activation of protein kinase A (PKA). PKA is known for its role in phosphorylating substrates, which could include OY-TES-1, thus enhancing its activity. Similarly, PMA acts as a direct activator of protein kinase C (PKC), which is capable of phosphorylating OY-TES-1, thereby potentially increasing its functional activity. Compounds like Epigallocatechin gallate inhibit certain kinases, which might clear the way for a higher degree of OY-TES-1 activity by reducing competitive phosphorylation. LY294002 and Wortmannin, both PI3K inhibitors, may alter downstream signaling in a way that favors the activation of OY-TES-1, although the precise mechanisms remain more oblique.
The activity of OY-TES-1 is further modulated through the influence of inhibitors of the MAPK pathway, such as PD98059 and SB203580, which target MEK and p38 MAPK, respectively. These inhibitors might shift signaling in a way that favors processes enhancing
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing the levels of cAMP. Elevated cAMP activates PKA, which can then phosphorylate proteins including OY-TES-1, enhancing its activity. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX is a non-selective inhibitor of phosphodiesterases, which degrade cAMP. By preventing cAMP degradation, IBMX indirectly increases PKA activity, which can enhance the phosphorylation state and activity of OY-TES-1. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which can phosphorylate and thus enhance the activity of OY-TES-1. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
This catechin inhibits certain kinases, potentially reducing competition for phosphorylation sites on OY-TES-1, thereby enhancing its activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor, which can lead to altered signaling downstream, potentially enhancing the activity of OY-TES-1 through less-defined feedback mechanisms. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is another PI3K inhibitor, working similarly to LY294002, to influence signaling pathways that could enhance the phosphorylation and activity of OY-TES-1. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a MEK inhibitor, which could alter the MAPK/ERK pathway and indirectly lead to enhanced activity of OY-TES-1 through complex signaling cascades. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor that could shift signaling pathways towards those that enhance the activity of OY-TES-1. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 is a calcium ionophore, which can increase intracellular calcium levels, activating calcium-dependent kinases and phosphatases that could enhance OY-TES-1 activity. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin is a SERCA pump inhibitor, increasing cytosolic calcium levels, and potentially enhancing OY-TES-1 activity through calcium-dependent signaling. | ||||||