OR9G9 Activators
Chemical activators of OR9G9 exhibit a range of interactions with the protein's structure, enabling the initiation of G-protein-coupled signaling pathways. For instance, Acetophenone, with its aromatic ketone group, can directly bind to the active site of OR9G9, which likely causes a conformational change facilitating the activation of the downstream signaling cascade. Similarly, Anisole can activate OR9G9 through the interaction of its methoxy group with the receptor, mimicking the natural ligand's structure and thus initiating the signal transduction process. Benzaldehyde, with its aldehyde group, is capable of binding to a reactive site on OR9G9, promoting an alteration in the receptor's tertiary structure that triggers the olfactory signal.
Furthermore, Cinnamaldehyde activates OR9G9 by its aldehyde group interacting with the receptor's binding site, leading to G-protein-mediated signal transduction. Ethyl Vanillin and Eugenol, with their respective vanillin ether group and allyl chain, can engage with OR9G9, inducing structural changes imperative for olfactory signaling. Isoeugenol's similarity to Eugenol suggests it can activate the receptor by interacting with the same binding site to initiate signal transduction. Terpenes like Limonene and Alpha-Pinene activate OR9G9 through their ability to bind to hydrophobic domains of the receptor; Limonene with its cyclic structure and Alpha-Pinene with its bicyclic terpene structure, both induce conformational changes that activate the signaling pathway. Methyl Salicylate, through its ester-binding region interaction, and Vanillin, through its aldehyde group, can trigger the G-protein signaling process. Lastly, Beta-Ionone's cyclic ketone structure allows it to bind to the receptor's active site, facilitating the activation of the associated signaling pathways without ambiguity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Acetophenone | 98-86-2 | sc-239189 | 5 g | $20.00 | ||
Acetophenone, through its aromatic ketone group, can directly activate OR9G9 by binding to the receptor's active site, thereby triggering a conformational change that stimulates the associated G-protein signaling cascade. | ||||||
Anisole | 100-66-3 | sc-233877 sc-233877A | 500 ml 2.5 L | $65.00 $204.00 | ||
Anisole activates OR9G9 by interaction with its methoxy group, which may mimic the natural ligand structure of the olfactory receptor, leading to receptor activation and subsequent signal transduction. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Cinnamaldehyde activates OR9G9 through its aldehyde group which can interact with the receptor's binding site, initiating signal transduction via the G-protein pathway. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
Ethyl Vanillin activates OR9G9 by engaging with the receptor due to its vanillin ether group, which can induce receptor conformational changes necessary for olfactory signaling. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol activates OR9G9 by binding to the receptor's active site, likely through its allyl chain, which leads to the activation of the G-protein signal transduction pathway. | ||||||
Isoeugenol | 97-54-1 | sc-250186 sc-250186A | 5 g 100 g | $62.00 $52.00 | ||
Isoeugenol can activate OR9G9 as its structure is similar to eugenol, potentially interacting with the same binding site on the receptor to initiate G-protein-coupled signal transduction. | ||||||
Dipentene | 138-86-3 | sc-252747 | 4 L | $120.00 | ||
Limonene activates OR9G9 through its cyclic terpene structure which can bind to the receptor's hydrophobic pocket, inducing a conformational change that activates the olfactory signal cascade. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Methyl Salicylate activates OR9G9 due to its ability to interact with the receptor's ester-binding region, triggering the G-protein-mediated signaling process. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $51.00 $113.00 | 2 | |
Alpha-Pinene activates OR9G9 through its bicyclic terpene structure which may interact with specific hydrophobic domains of the receptor, causing activation of the signal transduction pathway. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $43.00 $122.00 | 1 | |
Vanillin can activate OR9G9 by binding through its aldehyde group to the receptor, which is thought to trigger a cascade of conformational changes leading to olfactory signal transduction. | ||||||