Date published: 2026-5-30

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OR6M1 Inhibitors

Chemical inhibitors of OR6M1 are molecules that bind to the receptor's active site but do not activate the receptor; instead, they block the site and prevent activation by the endogenous ligand. Benzaldehyde, as an inhibitor, would occupy the binding site of OR6M1 and impede the conformational change necessary for activation, thereby preventing the receptor from signaling. Cinnamic aldehyde and eugenol, when acting as inhibitors, would competitively bind to the active site of OR6M1 without mimicking the natural ligands' activating effects. This binding would block the receptor's natural activation mechanism and inhibit the signaling pathway. Methyleugenol, thymol, and methyl salicylate could also act as inhibitors by interacting with the ligand-binding domain of OR6M1. While they can fit into the active site, as inhibitors, they would not lead to activation but rather obstruct the engagement of the receptor's natural ligand, thereby inhibiting activation. Citral, geraniol, and capsaicin, in the role of inhibitors, would bind to the receptor's active site without prompting a conformational change in the OR6M1 protein. This would prevent the activation of the signaling pathway that OR6M1 controls. Limonene, alpha-terpineol, and carvone, as inhibitors, would engage with the active site of OR6M1, blocking the receptor and maintaining it in an inactive state. This binding would prevent the conformational shift necessary for OR6M1 to become active, thus inhibiting the signaling cascade within the cell.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cinnamic Aldehyde

104-55-2sc-294033
sc-294033A
100 g
500 g
$104.00
$228.00
(0)

Cinnamic aldehyde competes with activating ligands for the OR6M1 binding site, leading to inhibition by preventing the conformational change required for OR6M1 activation.

Eugenol

97-53-0sc-203043
sc-203043A
sc-203043B
1 g
100 g
500 g
$32.00
$62.00
$218.00
2
(1)

Eugenol can inhibit OR6M1 by binding to the receptor's active site. By occupying this site, it prevents the proper ligands from initiating the receptor activity, thereby inhibiting OR6M1 function.

Thymol

89-83-8sc-215984
sc-215984A
100 g
500 g
$97.00
$193.00
3
(0)

Thymol can inhibit OR6M1 by interacting with the ligand-binding site, preventing the necessary conformational change in OR6M1 for activation.

Methyl Salicylate

119-36-8sc-204802
sc-204802A
250 ml
500 ml
$47.00
$70.00
(1)

Methyl salicylate inhibits OR6M1 by binding to the receptor's active site, thereby blocking the natural ligands from binding and preventing activation of the signaling pathway.

Citral

5392-40-5sc-252620
1 kg
$212.00
(1)

Citral can inhibit OR6M1 by binding competitively to the active site of the receptor, which prevents the receptor from undergoing the conformational changes required for activation.

Geraniol

106-24-1sc-235242
sc-235242A
25 g
100 g
$45.00
$119.00
(0)

Geraniol acts as an inhibitor by binding to the OR6M1 receptor at the ligand-binding domain, preventing the activation and subsequent signaling that would normally occur with the natural ligands.

Capsaicin

404-86-4sc-3577
sc-3577C
sc-3577D
sc-3577A
50 mg
250 mg
500 mg
1 g
$96.00
$160.00
$240.00
$405.00
26
(1)

Capsaicin can inhibit OR6M1 by binding to the active site and preventing activation of the receptor by its natural ligands, thereby inhibiting the receptor's signaling pathway.

D-Limonene

5989-27-5sc-205283
sc-205283A
100 ml
500 ml
$84.00
$129.00
3
(1)

Limonene can inhibit OR6M1 by occupying the ligand-binding site, which inhibits the receptor's ability to be activated by its natural ligands, resulting in the inhibition of the signaling cascade normally triggered by OR6M1 activation.

(+)-Carvone

2244-16-8sc-239480
sc-239480A
5 ml
25 ml
$33.00
$84.00
2
(1)

Carvone can inhibit OR6M1 by interacting with the receptor's active site, preventing the ligand-induced activation that is necessary for OR6M1 to function, which results in the inhibition of the receptor's normal signaling process.