OR6C6 Activators
Chemical activators of OR6C6 include a variety of compounds that are primarily known for their presence in fragrant substances which can bind to the olfactory receptors and initiate a signal transduction pathway. Anethole, for instance, is a substance commonly found in anise and fennel, and it activates OR6C6 by fitting into the odorant-binding site of this G-protein coupled receptor (GPCR), inducing a conformational change necessary for signal propagation. Similarly, Isoamyl acetate, with its characteristic banana-like aroma, serves as a direct ligand for OR6C6. By binding to the active site of the receptor, Isoamyl acetate elicits an activation response, leading to the cascade of intracellular signaling that is fundamental to the olfactory perception mediated by OR6C6.
Benzaldehyde and Cinnamaldehyde, both aromatic compounds with distinct scents reminiscent of almonds and cinnamon respectively, engage with OR6C6 at its recognition site. This interaction activates the receptor via the GPCR pathway, which is central to the protein's olfactory signaling function. Eucalyptol, another activator, is found in eucalyptus and activates OR6C6 by binding to the ligand-binding domain, triggering conformational changes that lead to GPCR pathway activation. Geraniol, a sweet-smelling alcohol found in rose oil and palmarosa, also activates OR6C6 through its interaction at the ligand-binding domain, prompting the GPCR cascade. Methyl anthranilate, which has a grape-like odor, binds and activates OR6C6, initiating the GPCR signaling. Vanillin and Ethyl vanillin, reminiscent of vanilla, function as activators by engaging with the active site of OR6C6, which prompts the GPCR signaling sequence.
Lastly, Citral, a compound with a citrus scent, Limonene, which has a citrusy aroma, and Alpha-pinene, a constituent of pine resin, all activate OR6C6. They do so by binding to the receptor's active site, inducing a conformational change that triggers the GPCR signaling mechanism. Each of these chemicals, by directly interacting with OR6C6, plays a pivotal role in the precise mechanism of action that leads to the functional activation of the protein, thereby facilitating the sensory responses that are characteristic of olfactory perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $576.00 $316.00 | ||
Anethole activates OR6C6 by binding to the odorant-binding site of the protein, causing a conformational change that leads directly to the activation of the G-protein coupled receptor pathway. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate serves as a direct ligand for OR6C6, binding to the active site and inducing receptor activation, which in turn initiates the intracellular signaling cascade associated with OR6C6. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamaldehyde interacts with OR6C6 by binding to its active site, leading to the activation of the receptor and subsequent GPCR signaling events characteristic of OR6C6's function. | ||||||
1,8-Cineole | 470-82-6 | sc-485261 | 25 ml | $44.00 | 2 | |
Eucalyptol activates OR6C6 by binding to the ligand-binding domain, triggering a conformational change and activating the G-protein coupled receptor signaling pathway associated with OR6C6. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol, through its interaction with OR6C6 at the ligand-binding domain, activates the receptor and prompts the GPCR signaling cascade, which is a part of OR6C6's activation process. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin functions as an activator of OR6C6 by direct binding to the receptor's active site, which in turn triggers the G-protein coupled receptor signaling cascade inherent to OR6C6 activation. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
3-Ethoxy-4-hydroxybenzaldehyde activates OR6C6 by engaging with the receptor's active site, leading to the activation of the G-protein coupled receptor pathway that OR6C6 utilizes for signaling. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral activates OR6C6 through direct binding to its ligand-binding domain, causing a receptor conformational change and activation of the GPCR pathway characteristic of OR6C6's role in olfaction. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene activates OR6C6 by binding to the specific active site on the receptor, which induces a conformational change and initiates the subsequent GPCR signaling events. | ||||||
(−)-α-Pinene | 7785-26-4 | sc-239166 | 25 g | $43.00 | ||
Alpha-pinene activates OR6C6 by interacting with the ligand-binding site on the receptor, causing a conformational alteration that triggers the GPCR signaling pathway involved in OR6C6 activation. | ||||||