OR6C3 Activators
Chemical activators of OR6C3 include a variety of compounds that engage directly with this olfactory receptor to initiate a signaling cascade. Anethole, for instance, binds to the odorant-binding site of OR6C3, causing a conformational alteration that triggers the G-protein coupled receptor (GPCR) signaling pathway, an essential process for the functional activation of OR6C3. Similarly, isoamyl acetate serves as a ligand for OR6C3, binding to its active site to induce receptor activation and the subsequent intracellular GPCR pathway activation. Benzaldehyde and cinnamaldehyde both interact with OR6C3 by binding to its recognition site, activating the receptor through the GPCR pathway. This action is critical for the activation of olfactory receptor proteins like OR6C3.
Eucalyptol, geraniol, and methyl anthranilate activate OR6C3 through a shared mechanism: by binding to the receptor's active site and inducing a conformational change that triggers the GPCR pathway, culminating in the receptor's activation. Vanillin and ethyl vanillin also act as activators by directly binding to OR6C3 and initiating the GPCR signaling cascade. Citral engages with the ligand-binding domain of OR6C3, resulting in receptor activation via the same pathway. Furthermore, limonene and alpha-pinene activate OR6C3 by binding to the receptor's specific active site, invoking a conformational change that leads to the activation of the GPCR signaling events and, consequently, the activation of OR6C3. Each compound's interaction with the receptor is integral to the precise and efficient activation of OR6C3, leveraging its role in olfactory perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $576.00 $316.00 | ||
Anethole activates OR6C3 by binding to its odorant-binding site, leading to a conformational change that triggers the G-protein coupled receptor (GPCR) signaling pathway, which is known to be involved in the functional activation of olfactory receptors such as OR6C3. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate can serve as a ligand for OR6C3, directly engaging with the receptor's active site to induce activation and initiate the subsequent intracellular GPCR pathway, culminating in the activation of OR6C3. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamaldehyde can activate OR6C3 by directly binding to it, leading to a conformational change that activates the GPCR signaling pathway, which in turn activates the receptor. | ||||||
1,8-Cineole | 470-82-6 | sc-485261 | 25 ml | $44.00 | 2 | |
Eucalyptol binds to OR6C3, inducing a conformational change that triggers the GPCR pathway, resulting in the direct activation of the receptor. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol activates OR6C3 through direct interaction with the receptor's binding site, promoting a conformational change and activation of the GPCR pathway that OR6C3 is part of, leading to its functional activation. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin acts as an activator of OR6C3 by directly binding to its receptor site and initiating the GPCR signaling cascade that leads to receptor activation. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral can function as an activator by directly engaging with the ligand-binding domain of OR6C3, resulting in activation of the receptor through the GPCR signaling pathway. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
3-Ethoxy-4-hydroxybenzaldehyde binds to the ligand-binding site of OR6C3, triggering the GPCR pathway that is responsible for the activation of the receptor. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene activates OR6C3 by binding to its specific active site, causing a conformational change that triggers the downstream GPCR signaling events that lead to the receptor's activation. | ||||||
(−)-α-Pinene | 7785-26-4 | sc-239166 | 25 g | $43.00 | ||
Alpha-pinene interacts with OR6C3, binding to the receptor and inducing a conformational change that activates the GPCR pathway, which subsequently leads to the activation of OR6C3. | ||||||