OR56A3 Inhibitors
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A could induce hyperacetylation of histones at the promoter region of OR56A3, which may lead to a more relaxed chromatin state that paradoxically reduces access for transcriptional machinery, thereby downregulating OR56A3 expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
By inhibiting the activity of DNA methyltransferases, 5-Azacytidine can cause a decrease in DNA methylation at the OR56A3 gene locus, which might suppress the initiation of transcription and lead to a decrease in OR56A3 mRNA synthesis. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Mithramycin A binds tightly to GC-rich DNA sequences in the promoter regions of certain genes. If the OR56A3 gene has such regions, this binding could obstruct the assembly of transcriptional complexes, resulting in reduced OR56A3 transcription. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D may intercalate into DNA and sterically hinder RNA polymerase movement along the DNA template, which would reduce transcriptional elongation of the OR56A3 gene, leading to lower levels of OR56A3 mRNA and protein. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin (Sirolimus) specifically inhibits mTORC1 signaling, which is crucial for cap-dependent translation initiation. This inhibition could lead to a general decrease in protein synthesis, including a reduction in the translation of existing OR56A3 mRNA molecules. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $62.00 $112.00 $214.00 $342.00 | 74 | |
By blocking EGFR tyrosine kinase activity, Gefitinib could suppress downstream signaling pathways that may be involved in the transcriptional upregulation of OR56A3, thereby decreasing its expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is known to have antioxidant properties and can inhibit the phosphorylation of signaling molecules. This could lead to a downregulation of OR56A3 expression if the gene is normally upregulated by oxidative stress or related signaling cascades. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has been shown to downregulate the expression of certain genes by inhibiting nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB). If NF-κB is involved in the upregulation of OR56A3, curcumin could reduce OR56A3 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol could enhance the deacetylase activity of SIRT1 on histones at the OR56A3 promoter. Enhanced deacetylation may lead to tighter chromatin compaction and, thus, a decrease in OR56A3 gene transcription. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY 294002 inhibits phosphatidylinositol 3-kinase (PI3K), potentially leading to reduced phosphorylation and activation of downstream proteins involved in cell survival and growth, including pathways that might otherwise upregulate OR56A3 expression. | ||||||