OR52J3 Activators
OR52J3 engage with the olfactory receptor in a manner that is precise and consistent with their molecular structures and the unique scent profiles they represent. When isoamyl acetate, with its distinctive banana-like aroma, comes into contact with OR52J3, it binds to the receptor's specific site, which instigates a structural transformation in the protein. This conformational change is what initiates the signaling through the G-protein coupled receptor (GPCR) pathway, leading to neuronal activation that is ultimately perceived as smell. Similarly, eugenol, which imparts a spicy clove scent, and citral that offers a lemony fragrance, both activate OR52J3 by interacting with its ligand-binding domain. The resulting alteration in the receptor's structure sets off a cascade of GPCR signaling, culminating in olfactory perception.
Benzaldehyde and geraniol both bind to OR52J3, inducing a change in the receptor's shape that triggers the associated GPCR signaling mechanisms integral to the sense of smell. Benzaldehyde is the key ingredient behind the almond aroma, while geraniol contributes to the distinctive smells of rose oil and palmarosa oil. Methyl salicylate and anethole, the compounds known for their wintergreen and anise scents, respectively, activate OR52J3 by modifying the protein's conformation, which leads to the activation of olfactory-related GPCR pathways. Likewise, cinnamaldehyde, limonene, hexanal, phenethyl alcohol, and alpha-pinene, each with their own unique scents ranging from cinnamon to citrus, freshly cut grass, floral notes, and pine, bind to the OR52J3 receptor. This binding results in conformational changes of the protein, effectively activating the downstream GPCR signaling involved in odor detection and the transmission of olfactory signals.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
This ester is known for its fruity banana-like scent and is used as a flavoring agent. In the context of OR52J3, isoamyl acetate activates the olfactory receptor by binding to the specific site on the protein, initiating a conformational change that triggers the G-protein coupled receptor (GPCR) signaling pathway leading to neuronal activation. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol, a component of clove oil, has a spicy aroma. It activates OR52J3 by interacting with the receptor's ligand-binding domain, causing an alteration in the receptor's structure and leading to activation of downstream GPCR signaling cascades, which results in the transmission of olfactory signals. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, a compound found in lemon and other citrus oils, is known for its lemon scent. It specifically activates OR52J3 by binding to it and inducing a change in its conformation, which in turn activates the GPCR pathway responsible for olfactory perception. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol gives rose oil and palmarosa oil their distinctive smells. It activates OR52J3 by docking to the receptor's ligand-binding region, inducing a change in receptor configuration that activates the GPCR pathway and thus initiates olfactory signal transduction. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
This chemical, known for its wintergreen scent, activates OR52J3 by binding to the receptor, which then undergoes a structural change, activating the GPCR signaling cascade that is integral to the sense of smell. | ||||||
Anethole | 104-46-1 | sc-481571A sc-481571 | 10 g 100 g | $576.00 $316.00 | ||
Anethole is a key component of anise and fennel. It activates OR52J3 by interacting with the receptor site, modifying the protein's shape, and leading to the activation of olfactory-related GPCR pathways. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Found in cinnamon oil, cinnamaldehyde activates OR52J3 by binding to the protein and causing a conformational shift that results in the activation of the GPCR signaling pathway, which is involved in the olfactory process. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene, with its characteristic citrus scent, activates OR52J3 by binding to the ligand-binding domain, inducing a conformational change in the receptor, and activating the downstream GPCR signaling involved in odor detection. | ||||||
Hexanal | 66-25-1 | sc-252885 | 2 ml | $27.00 | ||
Hexanal, which contributes to the smell of freshly cut grass, activates OR52J3 by attaching to the receptor and inducing a structural change that triggers the GPCR signaling pathway associated with olfactory sensation. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
Associated with a floral rose-like scent, phenethyl alcohol activates OR52J3 by binding to the receptor's active site, promoting a structural change in the protein that leads to activation of the GPCR signaling pathway. | ||||||