Date published: 2026-3-3

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OR51S1 Activators

OR51S1 function through a variety of molecular interactions, each initiating a distinct signaling cascade resulting in the activation of this G-protein coupled receptor (GPCR). Benzaldehyde engages with OR51S1 by docking onto the receptor's binding site, inducing a structural reconfiguration that triggers signal transduction, characterized by an increase in intracellular calcium levels. Eucalyptol and geraniol follow a similar pattern, with each molecule precisely fitting into the OR51S1 binding pocket, promoting activation of the associated G-protein and initiating a signaling cascade. Citronellal, phenethyl alcohol, and isoamyl acetate also act as OR51S1 agonists, each binding to the receptor's odorant-binding region, which leads to the activation of downstream G-protein pathways, upon which the activation of OR51S1 follows.

Anisaldehyde, methyl salicylate, and cinnamaldehyde activate OR51S1 by binding to the receptor's ligand-specific domain, setting off a series of intracellular events involving G-proteins. This results in a change in receptor conformation and the activation of OR51S1. Similarly, menthol, ethyl vanillin, and limonene serve as activators of OR51S1, with each compound engaging with the receptor's ligand-binding domain, initiating a signal transduction pathway through G-protein activation, culminating in the functional activation of OR51S1. These molecular interactions illustrate the diverse yet specific ways in which different chemicals can initiate the activation of OR51S1 through direct binding and subsequent G-protein mediated signal transduction pathways.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

1,8-Cineole

470-82-6sc-485261
25 ml
$44.00
2
(0)

Eucalyptol interacts with OR51S1 by binding to its specific odorant-binding site, triggering a signaling cascade involving G-protein activation, which results in the functional activation of OR51S1.

Geraniol

106-24-1sc-235242
sc-235242A
25 g
100 g
$45.00
$119.00
(0)

Geraniol binds to the ligand-binding domain of OR51S1, activating the receptor and resulting in a downstream signaling cascade that promotes the functional activation of OR51S1.

(±)-Citronellal

106-23-0sc-234400
100 ml
$51.00
(0)

Citronellal serves as an agonist for OR51S1 by fitting into the ligand-binding pocket, causing an activation of the G-protein coupled receptor pathway, which in turn leads to the functional activation of OR51S1.

2-Phenylethanol

60-12-8sc-238198
250 ml
$69.00
(0)

2-Phenylethanol activates OR51S1 by interacting with its odorant-binding region, leading to signal transduction through activation of associated G-proteins, ultimately resulting in the functional activation of the protein.

Isopentyl acetate

123-92-2sc-250190
sc-250190A
100 ml
500 ml
$107.00
$225.00
(0)

Isoamyl acetate binds to and activates OR51S1, initiating a signal transduction mechanism that involves G-protein activation and results in the functional activation of the receptor.

4-Methoxybenzaldehyde

123-11-5sc-238884
sc-238884A
sc-238884B
sc-238884C
5 g
100 g
250 g
1 kg
$30.00
$42.00
$72.00
$124.00
(1)

Anisaldehyde specifically binds to OR51S1, causing a conformational change that triggers signal transduction pathways, leading to the functional activation of this G-protein coupled receptor.

Methyl Salicylate

119-36-8sc-204802
sc-204802A
250 ml
500 ml
$47.00
$70.00
(1)

Methyl salicylate interacts with OR51S1, binding to its active site and initiating a signaling cascade through the G-protein coupled receptor mechanism, resulting in the functional activation of OR51S1.

Cinnamic Aldehyde

104-55-2sc-294033
sc-294033A
100 g
500 g
$104.00
$228.00
(0)

Cinnamaldehyde activates OR51S1 through binding to the receptor's ligand-specific domain, causing a signaling cascade that involves the activation of G-proteins and leading to the functional activation of the receptor.

(±)-Menthol

89-78-1sc-250299
sc-250299A
100 g
250 g
$39.00
$68.00
(0)

Menthol acts as an agonist to OR51S1 by binding to the receptor's ligand-binding domain, initiating a G-protein coupled signal transduction pathway that leads to the functional activation of OR51S1.

3-Ethoxy-4-hydroxybenzaldehyde

121-32-4sc-238538
100 g
$31.00
(0)

3-Ethoxy-4-hydroxybenzaldehyde activates OR51S1 by ligand-receptor binding, causing a change in receptor conformation, which in turn triggers a G-protein signaling cascade leading to the functional activation of OR51S1.