OR4D5 Activators
OR4D5 can initiate a complex process of olfactory detection through a series of molecular interactions. Isoamyl acetate, for instance, binds to OR4D5, causing a conformational change in the protein structure, which in turn leads to the activation of G proteins associated with the receptor. Similarly, benzaldehyde's interaction with OR4D5 sets off a cascade of intracellular events characteristic of G protein-coupled receptor (GPCR) mechanisms, ultimately leading to the depolarization of sensory neurons. The chemical 2-Heptanone engages with OR4D5's ligand-binding domain, triggering the olfactory signal transduction process. Eugenol and geranyl acetate also activate OR4D5 by fitting into the active site, promoting GPCR-mediated signal transduction pathways that culminate in the activation of olfactory sensory neurons.
Further elaborating on the diversity of chemical interactions, citronellol directly binds to OR4D5, which results in GPCR conformational changes and downstream signaling. Phenethyl alcohol activates OR4D5 by interacting with the binding site, causing an allosteric change that initiates G protein signaling. Methyl salicylate engages with the sensory domain of OR4D5, leading to the activation of the olfactory neural circuit. Ethyl butyrate, cinnamaldehyde, and anisaldehyde all activate OR4D5 through ligand-receptor binding, which induces conformational changes and initiates G protein-coupled responses that are crucial for transmitting olfactory signals. Lastly, limonene's specific interaction with OR4D5 facilitates the activation of G proteins, which are essential for the propagation of sensory signals that contribute to the sense of smell. Each chemical, by its unique molecular structure, aligns with the OR4D5 binding site, allowing for the precise activation of this olfactory receptor and the resulting sensory perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate activates OR4D5 by binding to the olfactory receptor, which is a G protein-coupled receptor (GPCR), leading to a conformational change and activation of the G protein, resulting in signal transduction and a sensory response. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone activates OR4D5 by interacting with the olfactory receptor's ligand-binding domain, causing activation of associated G proteins, and initiating olfactory signal transduction. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol activates OR4D5 by engaging with the receptor's active site, leading to GPCR-mediated signal transduction pathways, which result in olfactory sensory neuron activation. | ||||||
Geranyl acetate | 105-87-3 | sc-235243 | 25 g | $41.00 | ||
Geranyl acetate activates OR4D5 by binding specifically to the olfactory receptor, which triggers a change in receptor conformation and subsequent G protein activation, leading to sensory signal transduction. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $32.00 $156.00 | ||
Citronellol activates OR4D5 by directly binding to the receptor, promoting GPCR conformational change and activation, which in turn leads to downstream signaling involved in olfactory perception. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol activates OR4D5 by fitting into the binding site of the receptor, causing an allosteric change that leads to G protein signaling and subsequent neuronal activation in the olfactory system. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate activates OR4D5 through its interaction with the receptor's sensory domain, leading to GPCR-mediated signaling pathways and activation of the olfactory neural circuit. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate activates OR4D5 by ligand-receptor binding, which induces a G protein-coupled response, resulting in the transmission of olfactory signals to the brain. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamaldehyde activates OR4D5 by directly interacting with the olfactory receptor, triggering a GPCR mechanism that leads to the activation of olfactory signal transduction pathways. | ||||||
4-Methoxybenzaldehyde | 123-11-5 | sc-238884 sc-238884A sc-238884B sc-238884C | 5 g 100 g 250 g 1 kg | $30.00 $42.00 $72.00 $124.00 | ||
Anisaldehyde activates OR4D5 by binding to the receptor and inducing conformational changes that lead to the activation of the associated G protein and subsequent sensory response in the olfactory system. | ||||||