OR4D11 Activators
OR4D11 include a variety of compounds that are primarily associated with distinct odors. These activators, such as benzaldehyde, eugenol, isoamyl acetate, and limonene, can effectively bind to the OR4D11 receptor. Upon binding, these molecules induce a conformational change within the protein structure of OR4D11. This conformational change is a crucial initial step, as it triggers the receptor's ability to activate the associated G-protein. Once the G-protein is activated, it begins a signaling cascade within the olfactory neuron. Benzaldehyde, with its almond-like scent, and eugenol, found in clove oil, both serve as examples of how diverse aromatic compounds can engage with the same receptor, leading to the activation of G-protein and subsequent signal transduction. Similarly, isoamyl acetate, known for its banana scent, and limonene, with a citrus smell, also bind to OR4D11 and activate the signaling pathway, each contributing to the perception of their unique odors.
Other chemicals such as methyl salicylate, hexanal, alpha-pinene, and ethyl butyrate further illustrate the versatility of OR4D11 in recognizing and responding to a wide array of odorant molecules. Methyl salicylate, which emits a wintergreen odor, and hexanal, with a grassy fragrance, also interact with OR4D11, resulting in the activation of olfactory signal transduction pathways. Alpha-pinene, which has a pine aroma, and ethyl butyrate, noted for its fruity smell, similarly engage with OR4D11, leading to the activation of the G-protein coupled receptor pathway. This process is not exclusive to these compounds, as linalool, geraniol, citral, and beta-caryophyllene also bind to OR4D11. Linalool, recognized for its floral scent, geraniol with a rose-like fragrance, citral exuding a lemon scent, and beta-caryophyllene known for its spicy aroma, all demonstrate the ability of OR4D11 to interact with a spectrum of odorants, each initiating a unique sensory response through the same fundamental mechanism of G-protein receptor activation and signal transduction within the olfactory system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol, a compound found in clove oil, is capable of binding and activating olfactory receptors like OR4D11. Upon binding, it activates the associated G-protein and initiates a signaling cascade, resulting in a sensory response to the scent. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isoamyl acetate is a banana-scented ester that can activate olfactory receptors such as OR4D11. Its binding to the protein triggers the G-protein signaling pathway, leading to neuronal excitation in the olfactory system. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene, a citrus scent component, can activate certain olfactory receptors including OR4D11. Activation occurs through binding to the receptor, causing a signaling cascade involving G-protein activation and cellular response in the olfactory epithelium. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate, with a wintergreen odor, can activate olfactory receptors such as OR4D11. By binding to the receptor, it initiates G-protein coupled receptor signaling, leading to sensory perception of its scent. | ||||||
Hexanal | 66-25-1 | sc-252885 | 2 ml | $27.00 | ||
Hexanal, an aldehyde with a grassy odor, is known to activate olfactory receptors. When hexanal binds to OR4D11, it activates the receptor and its downstream G-protein signaling pathway, which is tied to the perception of its distinct smell. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
Alpha-Pinene, a terpene with a pine-like aroma, can activate olfactory receptors like OR4D11. Its interaction with the receptor triggers a G-protein coupled signaling process, resulting in the activation of the olfactory sensory neurons. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate, which has a fruity odor, can activate olfactory receptors such as OR4D11. Binding of this ester to the receptor leads to G-protein activation and subsequent signal transduction in olfactory pathways. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool, a floral-scented terpene alcohol, can activate olfactory receptors including OR4D11. The activation mechanism involves binding to the receptor, followed by triggering of the G-protein signaling cascade specific to olfactory sensory neurons. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol, a rose-scented monoterpenoid, is able to activate olfactory receptors. Upon binding to OR4D11, it activates the receptor and induces a signaling pathway involving G-protein activation, characteristic of olfactory perception. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral, with a strong lemon scent, can bind and activate olfactory receptors such as OR4D11. This binding directly results in the activation of the receptor, triggering a G-protein coupled signaling pathway and the sensing of its scent. | ||||||