OR13J1 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cromolyn disodium salt | 15826-37-6 | sc-207459 sc-207459A sc-207459B sc-207459C sc-207459D sc-207459E sc-207459F | 1 g 5 g 25 g 50 g 100 g 500 g 1 kg | $49.00 $171.00 $612.00 $1020.00 $1836.00 $2856.00 $3468.00 | ||
This compound stabilizes mast cells, preventing the release of pro-inflammatory mediators that can modulate olfactory receptor function. The decreased inflammatory response indirectly inhibits OR13J1 by ensuring the olfactory epithelium remains less inflamed and more selective to specific odorant molecules that OR13J1 is meant to detect. | ||||||
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $45.00 $120.00 $185.00 | 3 | |
Can lead to reduced function of OR13J1 receptors by causing local inflammation and direct harm to olfactory sensory neurons. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc ions have been shown to bind to olfactory receptor sites and alter their conformation. By changing the receptor conformation, zinc sulfate can indirectly inhibit the function of OR13J1 by preventing the binding of odorant molecules to the receptor. | ||||||
Methimazole | 60-56-0 | sc-205747 sc-205747A | 10 g 25 g | $69.00 $110.00 | 4 | |
As a thiourea analog, this compound can interfere with the proper folding and function of proteins by altering disulfide bond formation. Methimazole could indirectly inhibit OR13J1 by affecting its conformation or stability, thus diminishing its ability to interact with odorant ligands. | ||||||
2,4-Dinitrophenol, wetted | 51-28-5 | sc-238345 | 250 mg | $58.00 | 2 | |
This chemical uncouples oxidative phosphorylation, thereby disrupting ATP synthesis. As a consequence, the decreased cellular energy levels could indirectly inhibit OR13J1 function by impairing the energy-dependent processes required for olfactory signal transduction. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Known for its ability to activate TRPV1 receptors, capsaicin can cause a local inflammatory response in the olfactory epithelium that could indirectly inhibit OR13J1 by altering the tissue environment and potentially causing a decrease in receptor expression or function due to inflammatory mediators. | ||||||
Allyl isothiocyanate | 57-06-7 | sc-252361 sc-252361A sc-252361B | 5 g 100 g 500 g | $43.00 $66.00 $117.00 | 3 | |
Can activate TRPA1 receptors. If localized to the olfactory epithelium, allyl isothiocyanate could indirectly inhibit OR13J1 by causing inflammation and possibly reducing the sensitivity or expression of the receptor due to changes in the tissue environment. | ||||||
Ethylene glycol | 107-21-1 | sc-257515 sc-257515A | 500 ml 1 L | $83.00 $118.00 | 1 | |
A small organic molecule that, upon metabolism, can lead to metabolic acidosis and central nervous system depression. These systemic effects could indirectly inhibit OR13J1 by altering the physiological state of the olfactory sensory neurons, potentially affecting their ability to transduce signals. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $55.00 $179.00 $345.00 | 1 | |
Cadmium is a heavy metal that can cause olfactory dysfunction by damaging olfactory sensory neurons through apoptosis or necrosis. The resultant cellular damage could indirectly inhibit OR13J1 by reducing the number of functional olfactory receptors, including OR13J1, available to bind to odorant ligands. | ||||||