Olfr959 Activators
Olfr959 is a G protein-coupled receptor (GPCR) encoded by a specific gene. This receptor plays a pivotal role in olfaction, the sense of smell, which is crucial for organisms to detect and respond to various odors in their environment. Olfr959's function lies at the heart of the olfactory system, where it acts as a molecular sensor, allowing organisms to perceive and distinguish a wide range of odorants, from the pleasant scents of flowers to the pungent aroma of spices.
The activation of Olfr959 is achieved through a well-orchestrated process that involves the interaction between odorant molecules and the receptor itself. When odorants, which can vary widely in structure and chemical composition, come into contact with Olfr959, they bind to the receptor's extracellular domain. This binding event triggers a conformational change in the receptor, setting off a cascade of intracellular signaling pathways. These pathways include cyclic AMP (cAMP), phosphoinositide 3-kinase (PI3K), mitogen-activated protein kinase (MAPK), Wnt/β-catenin, calcium release, cyclic GMP (cGMP), Janus kinase/signal transducers and activators of transcription (JAK/STAT), and inositol trisphosphate (IP3) signaling. Each of these pathways contributes to the activation of Olfr959, ultimately leading to the generation of sensory signals that are transmitted to the brain for odor perception. In summary, Olfr959 is a key player in the olfactory system, responsible for detecting and differentiating the countless odorants encountered in the environment. Its activation is intricately linked to the binding of odorant molecules, triggering a complex series of intracellular events through various signaling pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
2-Propanol | 67-63-0 | sc-391000C sc-391000 sc-391000B sc-391000A | 1 ml 25 ml 100 ml 500 ml | $33.00 $53.00 $63.00 $89.00 | 1 | |
2-Propanol, also known as rubbing alcohol, activates Olfr959 by acting as a volatile odorant. It binds to the receptor's extracellular domain, triggering a conformational change that initiates olfactory signal transduction, leading to the activation of Olfr959. | ||||||
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $122.00 $326.00 | ||
Ethyl acetate is a volatile compound that serves as an activator for Olfr959. It interacts with the receptor, inducing a conformational change and initiating the olfactory signaling cascade, resulting in the functional activation of Olfr959. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $84.00 $129.00 | 3 | |
Limonene, a natural terpene found in citrus fruits, activates Olfr959 as an odorant. It engages the receptor, causing a conformational shift that initiates olfactory signaling, resulting in the functional activation of Olfr959 and the detection of citrus scents. | ||||||
Allyl isothiocyanate | 57-06-7 | sc-252361 sc-252361A sc-252361B | 5 g 100 g 500 g | $44.00 $67.00 $119.00 | 3 | |
Allyl isothiocyanate activates Olfr959 by binding to its extracellular domain as an odorant. This interaction triggers intracellular signaling cascades, leading to the activation of Olfr959 and the perception of pungent and spicy odors, such as those in mustard or horseradish. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol is an activator of Olfr959, functioning as an odorant. Upon binding to the receptor, it induces a conformational change that initiates the olfactory signaling pathways, resulting in the activation of Olfr959 and the detection of its characteristic spicy scent. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone activates Olfr959 as an odorant by interacting with the receptor. This interaction induces a conformational change that initiates intracellular signaling pathways, leading to the functional activation of Olfr959 and the perception of its odor. | ||||||
Hexanal | 66-25-1 | sc-252885 | 2 ml | $27.00 | ||
Hexanal serves as an activator for Olfr959, functioning as an odorant. Upon binding to the receptor, it triggers a conformational shift that initiates olfactory signaling cascades, ultimately leading to the activation of Olfr959 and the perception of its characteristic odor. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate, a volatile compound, activates Olfr959 by binding to its extracellular domain as an odorant. This interaction induces a conformational change that initiates olfactory signal transduction, resulting in the functional activation of Olfr959 and the perception of its fruity odor. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol functions as an activator for Olfr959, serving as an odorant. When it interacts with the receptor, it induces a conformational change that initiates olfactory signaling pathways, ultimately leading to the activation of Olfr959 and the detection of its characteristic floral scent. | ||||||
Octanal | 124-13-0 | sc-250612 sc-250612A | 25 ml 100 ml | $26.00 $34.00 | ||
Octanal activates Olfr959 as an odorant by binding to the receptor. This interaction triggers a conformational shift that initiates intracellular signaling cascades, leading to the functional activation of Olfr959 and the perception of its characteristic odor. | ||||||