Olfr938 Activators
Olfr938 is a member of the olfactory receptor family, specifically belonging to the class of G protein-coupled receptors (GPCRs). These receptors are key components in the olfactory system, responsible for the detection and perception of a wide range of odorants. The functional activation of Olfr938, as with other olfactory receptors, is a critical aspect of the olfactory process, enabling the identification and differentiation of various smells. Upon the binding of a specific chemical activator, Olfr938 undergoes a conformational change that triggers a series of intracellular signaling events. This typically involves the activation of a G protein, which subsequently stimulates adenylyl cyclase, an enzyme that converts ATP to cyclic AMP (cAMP). The increase in cAMP levels activates protein kinase A (PKA), which phosphorylates various target proteins, leading to changes in cellular function and ultimately resulting in the generation of a nerve impulse that is transmitted to the brain, where it is interpreted as a specific smell.
The specificity of Olfr938 activation is determined by the structural compatibility between the receptor and the activating chemicals. Each chemical activator has a unique molecular structure that allows it to bind specifically to Olfr938, initiating the receptor's activation. This specificity is crucial for the accurate perception of smells, as it enables the olfactory system to distinguish between different odorants. The diversity of activators for Olfr938, which include compounds with floral, sweet, fruity, and minty aromas, reflects the receptor's role in detecting a broad spectrum of smells. Understanding the mechanisms of activation of olfactory receptors like Olfr938 is essential for comprehending the complex nature of olfactory signaling. It sheds light on how different smells are detected and discriminated, and how the olfactory system contributes to various physiological and behavioral responses. The study of receptors like Olfr938 continues to be a vital area of research in neurobiology and sensory sciences, providing insights into the complex nature of smell perception and the intricate signaling pathways involved in olfactory signal transduction.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Decanal | 112-31-2 | sc-234518 | 25 g | $43.00 | ||
Decanal activates Olfr938 by binding to the receptor, initiating a G protein-coupled receptor (GPCR) signaling pathway. This interaction leads to the activation of adenylyl cyclase, resulting in an increase in cyclic AMP (cAMP) levels. Elevated cAMP activates protein kinase A (PKA), essential for the functional activation of Olfr938 in olfactory sensory neurons. | ||||||
4-Methoxybenzaldehyde | 123-11-5 | sc-238884 sc-238884A sc-238884B sc-238884C | 5 g 100 g 250 g 1 kg | $30.00 $42.00 $72.00 $124.00 | ||
4-Methoxybenzaldehyde, known for its sweet and anise-like aroma, activates Olfr938 by directly interacting with the receptor. This binding triggers GPCR signaling, leading to an increase in adenylyl cyclase activity and subsequent rise in cAMP levels. The elevated cAMP is key for the functional activation of Olfr938, playing a significant role in the perception of anise-related odors. | ||||||
Isoeugenol | 97-54-1 | sc-250186 sc-250186A | 5 g 100 g | $63.00 $53.00 | ||
Isoeugenol, with its clove-like scent, activates Olfr938 through receptor interaction, triggering GPCR signaling. The activation of adenylyl cyclase and the increase in cAMP levels are crucial for the functional activation of Olfr938, contributing to its role in olfactory signal transduction. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $32.00 $156.00 | ||
Citronellol, possessing a rose-like aroma, activates Olfr938 by binding to the receptor, initiating GPCR-mediated signaling. This activation increases adenylyl cyclase activity, elevating cAMP production. Elevated cAMP levels are essential for the functional activation of Olfr938, enhancing its role in olfactory perception. | ||||||
Benzyl acetate | 140-11-4 | sc-252427 | 100 g | $30.00 | 1 | |
Benzyl acetate, known for its sweet and fruity aroma, activates Olfr938 by binding to the receptor and triggering GPCR signaling. The subsequent activation of adenylyl cyclase leads to an increase in cAMP levels. This increase is key for the functional activation of Olfr938, contributing to its role in the perception of sweet and fruity odors. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol, a component of clove oil, activates Olfr938 by directly interacting with the receptor. This interaction induces GPCR signaling, leading to the activation of adenylyl cyclase and a subsequent rise in cAMP levels. Elevated cAMP levels are essential for the functional activation of Olfr938, playing a significant role in olfactory signaling. | ||||||
Geranyl acetate | 105-87-3 | sc-235243 | 25 g | $41.00 | ||
Geranyl acetate, with a floral and fruity aroma, activates Olfr938 by binding to the receptor and initiating GPCR signaling. This signaling results in the activation of adenylyl cyclase and an increase in cAMP production. Elevated cAMP levels are vital for the functional activation of Olfr938, enhancing its role in olfactory perception. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate, known for its wintergreen scent, activates Olfr938 through receptor interaction, triggering GPCR signaling. The activation of adenylyl cyclase and the subsequent rise in cAMP levels are crucial for the functional activation of Olfr938, contributing to its role in the detection of minty odors. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool, a compound with a floral aroma, activates Olfr938 by binding to the receptor and initiating a GPCR-mediated signaling pathway. The stimulation of adenylyl cyclase and the increase in cAMP levels are key for the functional activation of Olfr938, playing a significant role in olfactory perception. | ||||||
cis-3,7-Dimethyl-2,6-octadien-1-ol | 106-25-2 | sc-234382 | 5 ml | $51.00 | ||
cis-3,7-Dimethyl-2,6-octadien-1-ol, with its sweet rose odor, activates Olfr938 by interacting with the receptor, triggering GPCR signaling. This activation stimulates adenylyl cyclase, leading to an increase in cAMP levels. Elevated cAMP is crucial for the functional activation of Olfr938, enhancing its role in the detection of floral odors. | ||||||