Olfr922 Activators
Olfr922, a member of the olfactory receptor protein family, plays an essential role in the olfactory system's ability to detect and differentiate various odorant molecules. As part of the G-protein coupled receptors (GPCRs) family, Olfr922 is crucial in converting chemical signals from the environment into neural signals, a process vital for the perception of odors. The functional activation of Olfr922, like other olfactory receptors, is initiated when specific chemical compounds, serving as odorants, bind to the receptor. This binding causes a conformational change in the protein, which is the key mechanism for initiating signal transduction. The interaction between Olfr922 and these odorant molecules is highly specific and dependent on the structural compatibility between the two. This specificity allows the olfactory system to detect a wide range of odors with precision. Upon binding of an odorant molecule such as isoamyl acetate or ethyl butyrate, Olfr922 undergoes a conformational change, which triggers the activation of associated G-proteins. This activation sets off a cascade of intracellular events, such as the production of secondary messengers including cyclic AMP (cAMP) and the increase in intracellular calcium levels. These secondary messengers are responsible for amplifying the olfactory signal, leading to the opening of ion channels and ultimately resulting in a neural response. This specificity of activation is crucial for the accurate perception of odors, allowing the olfactory system to discern a vast array of scents.
Furthermore, the range of chemicals capable of activating Olfr922 underscores the broad specificity characteristic of olfactory receptors. This enables the detection of various odorant molecules, each imparting a distinct olfactory experience. The precise interaction of these chemicals with Olfr922 is critical for the proper functioning of the olfactory system, facilitating accurate odor detection and perception. This intricate interaction is fundamental to our sense of smell, playing an essential role in our daily interactions with the environment and contributing significantly to our overall sensory experience.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isopentyl acetate activates Olfr922 by binding to its olfactory receptor sites, inducing a conformational change in the protein. This interaction triggers the activation of G-protein coupled signaling pathways, leading to increased intracellular calcium levels and cyclic AMP, crucial for the functional activation and signal transduction of Olfr922, enhancing the perception of its banana-like odor. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate, with its fruity aroma, activates Olfr922 through binding to its specific olfactory receptor sites. This binding induces a structural alteration in Olfr922, initiating the activation of G-protein coupled intracellular signaling pathways. These pathways, particularly those involving the elevation of cyclic AMP, are essential for the functional activation of Olfr922, facilitating olfactory signal transmission. | ||||||
Butyl acetate | 123-86-4 | sc-214637 sc-214637A | 1 ml 5 ml | $20.00 $77.00 | ||
Butyl acetate, known for its fruity and fresh scent, activates Olfr922 by binding to its olfactory receptor sites. This binding triggers a change in the receptor's conformation, activating associated G-protein coupled signaling pathways. These pathways, including the rise in intracellular calcium and cyclic AMP levels, are crucial for the functional activation and proper signal transduction of Olfr922. | ||||||
Ethyl hexanoate | 123-66-0 | sc-235049 | 5 ml | $50.00 | ||
Ethyl hexanoate activates Olfr922 by binding to its olfactory receptor sites, causing a conformational change in the receptor. This change facilitates the activation of G-protein coupled pathways, resulting in intracellular signaling events. The increase in cyclic AMP, particularly, is essential for the functional activation of Olfr922, playing a key role in the perception of ethyl hexanoate's fruity and floral odor. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl acetate, a compound with a fruity and green odor, activates Olfr922 by interacting with its specific olfactory receptor binding sites. This interaction causes a change in the receptor's structure, triggering the activation of G-protein coupled signal transduction pathways. The activation of these pathways, especially those involving cAMP, is vital for the functional activation of Olfr922, enhancing the perception of its scent. | ||||||
Propyl acetate | 109-60-4 | sc-250792 | 500 ml | $20.00 | ||
Propyl acetate activates Olfr922 through molecular binding at its specific olfactory receptor sites. This binding induces a conformational change in Olfr922, leading to the activation of downstream G-protein coupled pathways. These pathways are essential for the transduction of olfactory signals mediated by Olfr922, particularly the increase in cyclic AMP levels. | ||||||
Ethyl valerate | 539-82-2 | sc-215002 | 500 ml | $83.00 | ||
Ethyl valerate, known for its apple-like aroma, activates Olfr922 by binding to its olfactory receptor sites. This interaction induces a structural alteration in Olfr922, leading to the activation of G-protein coupled intracellular signaling pathways. The activation of these pathways, especially those resulting in the increase of intracellular calcium levels, is crucial for the functional activation of Olfr922. | ||||||
Methyl butyrate | 623-42-7 | sc-215339 sc-215339A | 1 kg 5 kg | $95.00 $210.00 | ||
Methyl butyrate, with its fruity and pineapple-like aroma, activates Olfr922 by interacting with its specific olfactory receptor sites. This binding induces a structural change in Olfr922, triggering the activation of G-protein coupled signaling pathways. The activation of these pathways, including increased intracellular calcium levels, is vital for the functional activation of the olfactory receptor Olfr922. | ||||||
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $120.00 $320.00 | ||
Ethyl acetate activates Olfr922 through binding to its olfactory receptor sites. This interaction induces a conformational change in the receptor, leading to the activation of G-protein coupled pathways. The subsequent intracellular signaling cascade, particularly the rise of cyclic AMP, is essential for the functional activation of Olfr922, contributing to the perception of its sweet and solvent-like aroma. | ||||||