Olfr921 Activators
Olfr921 is a critical component of the olfactory receptor protein family, playing a significant role in the olfactory system's capacity to detect and differentiate various odorant molecules. As a member of the G-protein coupled receptor (GPCR) family, Olfr921 is essential in the process of converting external chemical stimuli into neural signals, which is fundamental for the perception of scents. The functional activation of Olfr921, similar to other olfactory receptors, is initiated when specific odorant molecules bind to the receptor. This binding leads to a conformational change in the protein, the primary trigger for initiating the signal transduction pathway. The specificity of the interaction between Olfr921 and these odorant molecules is essential for the selective detection of odors. Each olfactory receptor, including Olfr921, possesses unique binding sites that are structurally compatible with particular odorant molecules. When molecules such as amyl acetate, benzyl acetate, or nonanal bind to Olfr921, they induce structural changes in the receptor. These changes trigger the activation of the receptor's associated G-proteins, leading to a series of intracellular signaling events. These events typically involve the generation of secondary messengers like cyclic AMP and an increase in intracellular calcium levels. These messengers amplify the olfactory signal, resulting in a neural response. This precise mechanism of activation allows the olfactory system to detect a wide range of odors accurately, demonstrating the complexity and efficiency of the system.
Moreover, Olfr921's ability to be activated by a variety of chemicals with distinct structural features highlights the broad specificity of olfactory receptors. This broad specificity enables the olfactory system to recognize and process a diverse array of odorant molecules, each providing a unique sensory experience. The exact interaction of these chemicals with Olfr921 is crucial for the accurate functioning of the olfactory system, facilitating the detection and perception of odors. This interaction is fundamental to our sense of smell, significantly impacting our daily life and interactions with the environment, and contributing to our overall sensory experience.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pentyl acetate | 628-63-7 | sc-215691 | 250 ml | $65.00 | ||
Pentyl acetate activates Olfr921 by binding to its olfactory receptor sites, inducing a conformational change in the protein. This interaction triggers the activation of G-protein coupled signaling pathways, leading to increased intracellular calcium levels and cyclic AMP, crucial for the functional activation and signal transduction of Olfr921, enhancing the perception of its banana-like odor. | ||||||
Benzyl acetate | 140-11-4 | sc-252427 | 100 g | $29.00 | 1 | |
Benzyl acetate, with its sweet floral aroma, activates Olfr921 through binding to its specific olfactory receptor sites. This binding induces a structural alteration in Olfr921, initiating the activation of G-protein coupled intracellular signaling pathways. These pathways, particularly those involving the elevation of cyclic AMP, are essential for the functional activation of Olfr921, facilitating olfactory signal transmission. | ||||||
Isopentyl butyrate | 106-27-4 | sc-269267 | 100 g | $67.00 | ||
Isopentyl butyrate activates Olfr921 by interacting with its olfactory binding sites. This interaction results in a conformational change in Olfr921, leading to the activation of downstream G-protein coupled pathways. The activation of these pathways, especially those that increase cyclic AMP levels, is crucial for the functional activation and signal transduction of the olfactory receptor Olfr921. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl acetate, known for its fruity and green scent, activates Olfr921 by binding to its olfactory receptor sites. This binding triggers a change in the receptor's conformation, activating associated G-protein coupled signaling pathways. These pathways, including the rise in intracellular calcium and cyclic AMP levels, are crucial for the functional activation and proper signal transduction of Olfr921. | ||||||
Octyl acetate | 112-14-1 | sc-236244 | 5 g | $24.00 | ||
Octyl acetate, a compound with a fruity and slightly floral odor, activates Olfr921 by interacting with its specific olfactory receptor binding sites. This interaction causes a change in the receptor's structure, triggering the activation of G-protein coupled signal transduction pathways. The activation of these pathways, especially those involving cAMP, is vital for the functional activation of Olfr921, enhancing the perception of its scent. | ||||||
Nonanal | 124-19-6 | sc-257926 | 1 g | $66.00 | ||
Nonanal activates Olfr921 through molecular binding at its specific olfactory receptor sites. This binding induces a conformational change in Olfr921, leading to the activation of downstream G-protein coupled pathways. These pathways are essential for the transduction of olfactory signals mediated by Olfr921, particularly the increase in cyclic AMP levels. | ||||||
Decanal | 112-31-2 | sc-234518 | 25 g | $43.00 | ||
Decanal, known for its citrus-like aroma, activates Olfr921 by binding to its olfactory receptor sites. This interaction induces a structural alteration in Olfr921, leading to the activation of G-protein coupled intracellular signaling pathways. The activation of these pathways, especially those resulting in the increase of intracellular calcium levels, is crucial for the functional activation of Olfr921. | ||||||